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Diarylethene‐Based Photoswitchable Inhibitors of Serine Proteases

A bicyclic peptide scaffold was chemically adapted to generate diarylethene‐based photoswitchable inhibitors of serine protease Bos taurus trypsin 1 (T1). Starting from a prototype molecule—sunflower trypsin inhibitor‐1 (SFTI‐1)—we obtained light‐controllable inhibitors of T1 with K(i) in the low na...

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Detalles Bibliográficos
Autores principales:	Babii, Oleg, Afonin, Sergii, Diel, Christian, Huhn, Marcel, Dommermuth, Jennifer, Schober, Tim, Koniev, Serhii, Hrebonkin, Andrii, Nesterov‐Mueller, Alexander, Komarov, Igor V., Ulrich, Anne S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2021
Materias:	Communications
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519022/ https://www.ncbi.nlm.nih.gov/pubmed/34268844 http://dx.doi.org/10.1002/anie.202108847

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