A Convenient Formal [4+2] Heterocylization Route to Bis(triflyl)tetrahydroquinolines

We report the sustainable and efficient synthesis of a new type of quinoline derivatives bearing one or two SO(2)CF(3) groups. The protocol is metal‐, catalyst‐ and irradiation‐free, involves the use of readily available and stable precursors, and avoids the formation of side products. Also, the mil...

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Detalles Bibliográficos
Autores principales: Lázaro‐Milla, Carlos, Almendros, Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519061/
https://www.ncbi.nlm.nih.gov/pubmed/34369000
http://dx.doi.org/10.1002/chem.202102254
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author Lázaro‐Milla, Carlos
Almendros, Pedro
author_facet Lázaro‐Milla, Carlos
Almendros, Pedro
author_sort Lázaro‐Milla, Carlos
collection PubMed
description We report the sustainable and efficient synthesis of a new type of quinoline derivatives bearing one or two SO(2)CF(3) groups. The protocol is metal‐, catalyst‐ and irradiation‐free, involves the use of readily available and stable precursors, and avoids the formation of side products. Also, the mild conditions of the process allow the tolerance of a wide range of functional groups.
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spelling pubmed-85190612021-10-21 A Convenient Formal [4+2] Heterocylization Route to Bis(triflyl)tetrahydroquinolines Lázaro‐Milla, Carlos Almendros, Pedro Chemistry Communications We report the sustainable and efficient synthesis of a new type of quinoline derivatives bearing one or two SO(2)CF(3) groups. The protocol is metal‐, catalyst‐ and irradiation‐free, involves the use of readily available and stable precursors, and avoids the formation of side products. Also, the mild conditions of the process allow the tolerance of a wide range of functional groups. John Wiley and Sons Inc. 2021-08-10 2021-09-24 /pmc/articles/PMC8519061/ /pubmed/34369000 http://dx.doi.org/10.1002/chem.202102254 Text en © 2021 The Authors. Chemistry - A European Journal published by Wiley-VCH GmbH https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ (https://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Communications
Lázaro‐Milla, Carlos
Almendros, Pedro
A Convenient Formal [4+2] Heterocylization Route to Bis(triflyl)tetrahydroquinolines
title A Convenient Formal [4+2] Heterocylization Route to Bis(triflyl)tetrahydroquinolines
title_full A Convenient Formal [4+2] Heterocylization Route to Bis(triflyl)tetrahydroquinolines
title_fullStr A Convenient Formal [4+2] Heterocylization Route to Bis(triflyl)tetrahydroquinolines
title_full_unstemmed A Convenient Formal [4+2] Heterocylization Route to Bis(triflyl)tetrahydroquinolines
title_short A Convenient Formal [4+2] Heterocylization Route to Bis(triflyl)tetrahydroquinolines
title_sort convenient formal [4+2] heterocylization route to bis(triflyl)tetrahydroquinolines
topic Communications
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519061/
https://www.ncbi.nlm.nih.gov/pubmed/34369000
http://dx.doi.org/10.1002/chem.202102254
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