Design, Synthesis, Evaluation and Structure of Allenic 1α,25‐Dihydroxyvitamin D(3) Analogs with Locked Mobility at C‐17

Vitamin D receptor ligands have potential for the treatment of hyperproliferative diseases and disorders related to the immune system. However, hypercalcemic effects limit their therapeutical uses and call for the development of tissue‐selective new analogs. We have designed and synthesized the firs...

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Detalles Bibliográficos
Autores principales: Fraga, Ramón, Len, Kateryna, Lutzing, Regis, Laverny, Gilles, Loureiro, Julian, Maestro, Miguel A., Rochel, Natacha, Rodriguez‐Borges, Enrique, Mouriño, Antonio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Full Papers
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519077/
https://www.ncbi.nlm.nih.gov/pubmed/34224173
http://dx.doi.org/10.1002/chem.202101578

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519077/
https://www.ncbi.nlm.nih.gov/pubmed/34224173
http://dx.doi.org/10.1002/chem.202101578

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