MicroRNA‐34a activation in tuberous sclerosis complex during early brain development may lead to impaired corticogenesis

AIMS: Tuberous sclerosis complex (TSC) is a genetic disorder associated with dysregulation of the mechanistic target of rapamycin complex 1 (mTORC1) signalling pathway. Neurodevelopmental disorders, frequently present in TSC, are linked to cortical tubers in the brain. We previously reported microRN...

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Detalles Bibliográficos
Autores principales: Korotkov, Anatoly, Sim, Nam Suk, Luinenburg, Mark J., Anink, Jasper J., van Scheppingen, Jackelien, Zimmer, Till S., Bongaarts, Anika, Broekaart, Diede W. M., Mijnsbergen, Caroline, Jansen, Floor E., Van Hecke, Wim, Spliet, Wim G. M., van Rijen, Peter C., Feucht, Martha, Hainfellner, Johannes A., Kršek, Pavel, Zamecnik, Josef, Crino, Peter B., Kotulska, Katarzyna, Lagae, Lieven, Jansen, Anna C., Kwiatkowski, David J., Jozwiak, Sergiusz, Curatolo, Paolo, Mühlebner, Angelika, Lee, Jeong H., Mills, James D., van Vliet, Erwin A., Aronica, Eleonora
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519131/
https://www.ncbi.nlm.nih.gov/pubmed/33942341
http://dx.doi.org/10.1111/nan.12717

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