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Has COVID-19 changed the approach to HIV diagnosis?: A multicentric Italian experience

The occurrence of COVID-19 pandemic had a significant negative effect on health care systems over the last year. Health care providers were forced to focus mainly on COVID-19 patients, neglecting in many cases equally important diseases, both acute and chronic. Therefore, also screening and diagnost...

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Autores principales: Mazzitelli, Maria, Ciccullo, Arturo, Baldin, Gianmaria, Cauda, Roberto, Rusconi, Stefano, Giacomelli, Andrea, Oreni, Letizia, Borghi, Vanni, Mussini, Cristina, Guaraldi, Giovanni, Sterrantino, Gaetana, Lagi, Filippo, Candelaresi, Bianca, Cirioni, Oscar, De Vito, Andrea, Rossetti, Barbara, Torti, Carlo, Di Giambenedetto, Simona
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Lippincott Williams & Wilkins 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519218/
https://www.ncbi.nlm.nih.gov/pubmed/34731116
http://dx.doi.org/10.1097/MD.0000000000027418
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author Mazzitelli, Maria
Ciccullo, Arturo
Baldin, Gianmaria
Cauda, Roberto
Rusconi, Stefano
Giacomelli, Andrea
Oreni, Letizia
Borghi, Vanni
Mussini, Cristina
Guaraldi, Giovanni
Sterrantino, Gaetana
Lagi, Filippo
Candelaresi, Bianca
Cirioni, Oscar
De Vito, Andrea
Rossetti, Barbara
Torti, Carlo
Di Giambenedetto, Simona
author_facet Mazzitelli, Maria
Ciccullo, Arturo
Baldin, Gianmaria
Cauda, Roberto
Rusconi, Stefano
Giacomelli, Andrea
Oreni, Letizia
Borghi, Vanni
Mussini, Cristina
Guaraldi, Giovanni
Sterrantino, Gaetana
Lagi, Filippo
Candelaresi, Bianca
Cirioni, Oscar
De Vito, Andrea
Rossetti, Barbara
Torti, Carlo
Di Giambenedetto, Simona
author_sort Mazzitelli, Maria
collection PubMed
description The occurrence of COVID-19 pandemic had a significant negative effect on health care systems over the last year. Health care providers were forced to focus mainly on COVID-19 patients, neglecting in many cases equally important diseases, both acute and chronic. Therefore, also screening and diagnostic strategies for HIV could have been significantly impaired. This retrospective, multicenter, observational study aimed at assessing the number and characteristics of new HIV/AIDS diagnoses during COVID-19 pandemic in Italy and compared characteristics of people living with HIV at diagnosis between pre- and post-COVID-19 era (2019 vs 2020). Our results showed a significant reduction of HIV diagnoses during pandemic. By contrast, people living with HIV during pandemic were older and were diagnosed in earlier stage of disease (considering CD4+ T cell count) compared to those who were diagnosed the year before. Moreover, there was a significant decrease of new HIV diagnoses among men who have sex with men, probably for the impact of social distancing and restriction applied by the Italian Government. Late presentation incidence, if numbers in 2020 were lower than those in 2019, is still an issue. Routinely performing HIV testing in patients with suspected SARS-CoV-2 infection is identifying and linking to care underdiagnosed people living with HIV earlier. Thus, combined tests (HIV and SARS-CoV-2) should be implemented in patients with SARS-CoV-2 symptoms overlapping HIV's ones. Lastly, our results lastly showed how urgent implementation of a national policy for HIV screening is necessary.
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spelling pubmed-85192182021-10-18 Has COVID-19 changed the approach to HIV diagnosis?: A multicentric Italian experience Mazzitelli, Maria Ciccullo, Arturo Baldin, Gianmaria Cauda, Roberto Rusconi, Stefano Giacomelli, Andrea Oreni, Letizia Borghi, Vanni Mussini, Cristina Guaraldi, Giovanni Sterrantino, Gaetana Lagi, Filippo Candelaresi, Bianca Cirioni, Oscar De Vito, Andrea Rossetti, Barbara Torti, Carlo Di Giambenedetto, Simona Medicine (Baltimore) 4850 The occurrence of COVID-19 pandemic had a significant negative effect on health care systems over the last year. Health care providers were forced to focus mainly on COVID-19 patients, neglecting in many cases equally important diseases, both acute and chronic. Therefore, also screening and diagnostic strategies for HIV could have been significantly impaired. This retrospective, multicenter, observational study aimed at assessing the number and characteristics of new HIV/AIDS diagnoses during COVID-19 pandemic in Italy and compared characteristics of people living with HIV at diagnosis between pre- and post-COVID-19 era (2019 vs 2020). Our results showed a significant reduction of HIV diagnoses during pandemic. By contrast, people living with HIV during pandemic were older and were diagnosed in earlier stage of disease (considering CD4+ T cell count) compared to those who were diagnosed the year before. Moreover, there was a significant decrease of new HIV diagnoses among men who have sex with men, probably for the impact of social distancing and restriction applied by the Italian Government. Late presentation incidence, if numbers in 2020 were lower than those in 2019, is still an issue. Routinely performing HIV testing in patients with suspected SARS-CoV-2 infection is identifying and linking to care underdiagnosed people living with HIV earlier. Thus, combined tests (HIV and SARS-CoV-2) should be implemented in patients with SARS-CoV-2 symptoms overlapping HIV's ones. Lastly, our results lastly showed how urgent implementation of a national policy for HIV screening is necessary. Lippincott Williams & Wilkins 2021-10-15 /pmc/articles/PMC8519218/ /pubmed/34731116 http://dx.doi.org/10.1097/MD.0000000000027418 Text en Copyright © 2021 the Author(s). Published by Wolters Kluwer Health, Inc. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) This article is made available via the PMC Open Access Subset for unrestricted re-use and analyses in any form or by any means with acknowledgement of the original source. These permissions are granted for the duration of the COVID-19 pandemic or until permissions are revoked in writing. Upon expiration of these permissions, PMC is granted a perpetual license to make this article available via PMC and Europe PMC, consistent with existing copyright protections.
spellingShingle 4850
Mazzitelli, Maria
Ciccullo, Arturo
Baldin, Gianmaria
Cauda, Roberto
Rusconi, Stefano
Giacomelli, Andrea
Oreni, Letizia
Borghi, Vanni
Mussini, Cristina
Guaraldi, Giovanni
Sterrantino, Gaetana
Lagi, Filippo
Candelaresi, Bianca
Cirioni, Oscar
De Vito, Andrea
Rossetti, Barbara
Torti, Carlo
Di Giambenedetto, Simona
Has COVID-19 changed the approach to HIV diagnosis?: A multicentric Italian experience
title Has COVID-19 changed the approach to HIV diagnosis?: A multicentric Italian experience
title_full Has COVID-19 changed the approach to HIV diagnosis?: A multicentric Italian experience
title_fullStr Has COVID-19 changed the approach to HIV diagnosis?: A multicentric Italian experience
title_full_unstemmed Has COVID-19 changed the approach to HIV diagnosis?: A multicentric Italian experience
title_short Has COVID-19 changed the approach to HIV diagnosis?: A multicentric Italian experience
title_sort has covid-19 changed the approach to hiv diagnosis?: a multicentric italian experience
topic 4850
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519218/
https://www.ncbi.nlm.nih.gov/pubmed/34731116
http://dx.doi.org/10.1097/MD.0000000000027418
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