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Arglabin could target inflammasome-induced ARDS and cytokine storm associated with COVID-19
Arglabin (l(R),10(S)-epoxy-5(S),5(S),7(S)-guaia-3(4),ll(13)-dien-6,12-olide), is a natural sesquiterpene γ-lactone which was first isolated from Artemisia glabella. The compound has been shown to possess anti-inflammatory activity through inhibition of the NLR Family pyrin domain-containing 3 (NLRP3...
Autores principales: | Manayi, Azadeh, Nabavi, Seyed Mohammad, Khayatkashani, Maryam, Habtemariam, Solomon, Khayat Kashani, Hamid Reza |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Netherlands
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519322/ https://www.ncbi.nlm.nih.gov/pubmed/34655016 http://dx.doi.org/10.1007/s11033-021-06827-7 |
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