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Accuracy of Diagnostic Tests

Following the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, design, development, validation, verification and implementation of diagnostic tests were actively addressed by a large number of diagnostic test manufacturers. This paper deals with the biases and sources of variation which...

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Detalles Bibliográficos
Autores principales: Santini, Ario, Man, Adrian, Voidăzan, Septimiu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sciendo 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519382/
https://www.ncbi.nlm.nih.gov/pubmed/34722928
http://dx.doi.org/10.2478/jccm-2021-0022
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author Santini, Ario
Man, Adrian
Voidăzan, Septimiu
author_facet Santini, Ario
Man, Adrian
Voidăzan, Septimiu
author_sort Santini, Ario
collection PubMed
description Following the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, design, development, validation, verification and implementation of diagnostic tests were actively addressed by a large number of diagnostic test manufacturers. This paper deals with the biases and sources of variation which influence the accuracy of diagnostic tests, including calculating and interpreting test characteristics, defining what is meant by test accuracy, understanding the basic study design for evaluating test accuracy, understanding the meaning of Sensitivity, Specificity, Positive Predictive Value and Negative Predictive Value, and evaluating them numerically, and the ROC curve (or Receiver Operating Characteristic ) and the Area under the Curve (AUC).
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spelling pubmed-85193822021-10-28 Accuracy of Diagnostic Tests Santini, Ario Man, Adrian Voidăzan, Septimiu J Crit Care Med (Targu Mures) Spotlight On... Following the outbreak of the coronavirus disease 2019 (COVID-19) pandemic, design, development, validation, verification and implementation of diagnostic tests were actively addressed by a large number of diagnostic test manufacturers. This paper deals with the biases and sources of variation which influence the accuracy of diagnostic tests, including calculating and interpreting test characteristics, defining what is meant by test accuracy, understanding the basic study design for evaluating test accuracy, understanding the meaning of Sensitivity, Specificity, Positive Predictive Value and Negative Predictive Value, and evaluating them numerically, and the ROC curve (or Receiver Operating Characteristic ) and the Area under the Curve (AUC). Sciendo 2021-08-05 /pmc/articles/PMC8519382/ /pubmed/34722928 http://dx.doi.org/10.2478/jccm-2021-0022 Text en © 2021 Ario Santini, Adrian Man, Septimiu Voidăzan, published by Sciendo https://creativecommons.org/licenses/by-nc-nd/4.0/This work is licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
spellingShingle Spotlight On...
Santini, Ario
Man, Adrian
Voidăzan, Septimiu
Accuracy of Diagnostic Tests
title Accuracy of Diagnostic Tests
title_full Accuracy of Diagnostic Tests
title_fullStr Accuracy of Diagnostic Tests
title_full_unstemmed Accuracy of Diagnostic Tests
title_short Accuracy of Diagnostic Tests
title_sort accuracy of diagnostic tests
topic Spotlight On...
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519382/
https://www.ncbi.nlm.nih.gov/pubmed/34722928
http://dx.doi.org/10.2478/jccm-2021-0022
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