The pleiotropic roles of autophagy in Alzheimer's disease: From pathophysiology to therapy

Autophagy is a lysosomal degradation pathway and the main clearance route of many toxic protein aggregates. The molecular pathology of Alzheimer's disease (AD) manifests in the form of protein aggregates—extracellular amyloid-β depositions and intracellular tau neurofibrillary tangles. Perturba...

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Detalles Bibliográficos
Autores principales: Festa, Beatrice Paola, Barbosa, Antonio Daniel, Rob, Matea, Rubinsztein, David C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier Science Ltd 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519395/
https://www.ncbi.nlm.nih.gov/pubmed/34419832
http://dx.doi.org/10.1016/j.coph.2021.07.011

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519395/
https://www.ncbi.nlm.nih.gov/pubmed/34419832
http://dx.doi.org/10.1016/j.coph.2021.07.011

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