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miR-1 sustains muscle physiology by controlling V-ATPase complex assembly

Muscle function requires unique structural and metabolic adaptations that can render muscle cells selectively vulnerable, with mutations in some ubiquitously expressed genes causing myopathies but sparing other tissues. We uncovered a muscle cell vulnerability by studying miR-1, a deeply conserved,...

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Detalles Bibliográficos
Autores principales: Gutiérrez-Pérez, Paula, Santillán, Emilio M., Lendl, Thomas, Wang, Jingkui, Schrempf, Anna, Steinacker, Thomas L., Asparuhova, Mila, Brandstetter, Marlene, Haselbach, David, Cochella, Luisa
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Association for the Advancement of Science 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519577/
https://www.ncbi.nlm.nih.gov/pubmed/34652942
http://dx.doi.org/10.1126/sciadv.abh1434

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