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miR-1 sustains muscle physiology by controlling V-ATPase complex assembly
Muscle function requires unique structural and metabolic adaptations that can render muscle cells selectively vulnerable, with mutations in some ubiquitously expressed genes causing myopathies but sparing other tissues. We uncovered a muscle cell vulnerability by studying miR-1, a deeply conserved,...
Autores principales: | Gutiérrez-Pérez, Paula, Santillán, Emilio M., Lendl, Thomas, Wang, Jingkui, Schrempf, Anna, Steinacker, Thomas L., Asparuhova, Mila, Brandstetter, Marlene, Haselbach, David, Cochella, Luisa |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Association for the Advancement of Science
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519577/ https://www.ncbi.nlm.nih.gov/pubmed/34652942 http://dx.doi.org/10.1126/sciadv.abh1434 |
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