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Exosomes Derived from RM-1 Cells Promote the Recruitment of MDSCs into Tumor Microenvironment by Upregulating CXCR4 via TLR2/NF-κB Pathway

Myeloid-derived suppressor cells (MDSCs) play a critical role in tumor immune escape because of its remarkable immunosuppressive effect. However, the mechanism of MDSCs migrated into tumor microenvironment remains unclear. In this study, we demonstrated the recruitment of MDSCs can be promoted by ex...

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Detalles Bibliográficos
Autores principales:	Li, Nan, Wang, Yingying, Xu, Haoyu, Wang, Hexi, Gao, Yingying, Zhang, Yao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519695/ https://www.ncbi.nlm.nih.gov/pubmed/34659412 http://dx.doi.org/10.1155/2021/5584406

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