Intrapleural Tenecteplase for Complicated Parapneumonic Pleural Effusion

Intrapleural thrombolytics have shown promising results in complicated parapneumonic pleural effusions reducing the need for surgical interventions. Until now, studies have evaluated primarily streptokinase, urokinase, and recently, alteplase. In this case series, we share our experience with tenect...

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Autores principales: Kadhem, Husain, Sridharan, Kannan, Naser, Naser
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Case Series
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519699/
https://www.ncbi.nlm.nih.gov/pubmed/34659858
http://dx.doi.org/10.1155/2021/2206692
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author Kadhem, Husain
Sridharan, Kannan
Naser, Naser
author_facet Kadhem, Husain
Sridharan, Kannan
Naser, Naser
author_sort Kadhem, Husain
collection PubMed
description Intrapleural thrombolytics have shown promising results in complicated parapneumonic pleural effusions reducing the need for surgical interventions. Until now, studies have evaluated primarily streptokinase, urokinase, and recently, alteplase. In this case series, we share our experience with tenecteplase—a tissue-specific plasminogen activator in 15 patients. We observed that tenecteplase is effective in 14/15 (93.3%) of our patients, and none of them had any bleeding episodes.
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spelling pubmed-85196992021-10-16 Intrapleural Tenecteplase for Complicated Parapneumonic Pleural Effusion Kadhem, Husain Sridharan, Kannan Naser, Naser Case Rep Pulmonol Case Series Intrapleural thrombolytics have shown promising results in complicated parapneumonic pleural effusions reducing the need for surgical interventions. Until now, studies have evaluated primarily streptokinase, urokinase, and recently, alteplase. In this case series, we share our experience with tenecteplase—a tissue-specific plasminogen activator in 15 patients. We observed that tenecteplase is effective in 14/15 (93.3%) of our patients, and none of them had any bleeding episodes. Hindawi 2021-10-08 /pmc/articles/PMC8519699/ /pubmed/34659858 http://dx.doi.org/10.1155/2021/2206692 Text en Copyright © 2021 Husain Kadhem et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Series
Kadhem, Husain
Sridharan, Kannan
Naser, Naser
Intrapleural Tenecteplase for Complicated Parapneumonic Pleural Effusion
title Intrapleural Tenecteplase for Complicated Parapneumonic Pleural Effusion
title_full Intrapleural Tenecteplase for Complicated Parapneumonic Pleural Effusion
title_fullStr Intrapleural Tenecteplase for Complicated Parapneumonic Pleural Effusion
title_full_unstemmed Intrapleural Tenecteplase for Complicated Parapneumonic Pleural Effusion
title_short Intrapleural Tenecteplase for Complicated Parapneumonic Pleural Effusion
title_sort intrapleural tenecteplase for complicated parapneumonic pleural effusion
topic Case Series
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519699/
https://www.ncbi.nlm.nih.gov/pubmed/34659858
http://dx.doi.org/10.1155/2021/2206692
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AT sridharankannan intrapleuraltenecteplaseforcomplicatedparapneumonicpleuraleffusion
AT nasernaser intrapleuraltenecteplaseforcomplicatedparapneumonicpleuraleffusion

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