Cargando…

Based on UPLC-Q-TOF-MS/MS, Systematic Network Pharmacology, and Molecular Docking to Explore the Potential Mechanism of Fructus Aurantii for Major Depression Disorder

BACKGROUND: Major Depression Disorder (MDD) is a common mental disease that has become one of the world's major medical diseases. Currently, the Fructus Aurantii (FA) has been widely used to treat depression. However, the active substance ingredients and potential mechanisms of the shell antide...

Descripción completa

Detalles Bibliográficos
Autores principales:	Xie, Yating, Liu, Ying, Zheng, Peng, Zhang, Tao, Ye, Xianwen, Liu, Minmin, Huang, Min, Wan, Quan, Zhang, Jinlian
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519718/ https://www.ncbi.nlm.nih.gov/pubmed/34659436 http://dx.doi.org/10.1155/2021/6486287

Ejemplares similares

Identification and Comparison of Constituents of Aurantii Fructus and Aurantii Fructus Immaturus by UFLC-DAD-Triple TOF-MS/MS
por: Bai, Yang, et al.
Publicado: (2018)

Chemical Profiles and Simultaneous Quantification of Aurantii fructus by Use of HPLC-Q-TOF-MS Combined with GC-MS and HPLC Methods
por: He, Yingjie, et al.
Publicado: (2018)

Integrated Phytochemical Analysis Based on UPLC-Q-TOF-MS/MS, Network Pharmacology, and Experiment Verification to Explore the Potential Mechanism of Platycodon grandiflorum for Chronic Bronchitis
por: Deng, Yaling, et al.
Publicado: (2020)

Identification of Sanguinarine Metabolites in Rats Using UPLC-Q-TOF-MS/MS
por: Liu, Mengting, et al.
Publicado: (2023)

Drying kinetics and attributes of fructus aurantii processed by hot air thin-layer drying at different temperatures
por: Bai, Tingting, et al.
Publicado: (2023)

The Evaluation of Toxicity Induced by Psoraleae Fructus in Rats Using Untargeted Metabonomic Method Based on UPLC-Q-TOF/MS
por: Xu, Yanyan, et al.
Publicado: (2017)

Qualitative and Quantitative Analysis of the Major Constituents in Shexiang Tongxin Dropping Pill by HPLC-Q-TOF-MS/MS and UPLC-QqQ-MS/MS
por: Chen, Daxin, et al.
Publicado: (2015)

Systematic Analysis of Main Constituents in Rat Biological Samples after Oral Administration of the Methanol Extract of Fructus Aurantii by HPLC-ESI-MS/MS
por: Zhang, Jingze, et al.
Publicado: (2014)

Exploring potential mechanism of ciwujia tablets for insomnia by UPLC-Q-TOF-MS/MS, network pharmacology, and experimental validation
por: Liu, Hongda, et al.
Publicado: (2022)

Metabolite Profiling and Distribution of Militarine in Rats Using UPLC-Q-TOF-MS/MS
por: Li, Limin, et al.
Publicado: (2020)

Flavonoids from Aurantii Fructus Immaturus and Aurantii Fructus: promising phytomedicines for the treatment of liver diseases
por: Wu, Jianzhi, et al.
Publicado: (2020)

Simultaneous Analysis of Iridoid Glycosides and Anthraquinones in Morinda officinalis Using UPLC-QqQ-MS/MS and UPLC-Q/TOF-MS(E)
por: Zhao, Xiangsheng, et al.
Publicado: (2018)

Systematically Deciphering the Pharmacological Mechanism of Fructus Aurantii via Network Pharmacology
por: Jin, Qionglong, et al.
Publicado: (2021)

Integrated UPLC-Q-TOF-MS/MS and Network Pharmacology Approach to Investigating the Metabolic Profile of Marein of Coreopsis tinctoria Nutt.
por: Liu, Jing, et al.
Publicado: (2022)

Quality Evaluation of Tricholoma matsutake Based on the Nucleic Acid Compounds by UPLC-TOF/MS and UPLC-QqQ/MS
por: Xue, Ying, et al.
Publicado: (2018)

Identification of Antitumor Active Constituents in Polygonatum sibiricum Flower by UPLC-Q-TOF-MS(E) and Network Pharmacology
por: Huang, Zhuang-zhuang, et al.
Publicado: (2020)

Anti-melanoma activity of Forsythiae Fructus aqueous extract in mice involves regulation of glycerophospholipid metabolisms by UPLC/Q-TOF MS-based metabolomics study
por: Bao, Jiaolin, et al.
Publicado: (2016)

Combination of UPLC–Q-TOF/MS and Network Pharmacology to Reveal the Mechanism of Qizhen Decoction in the Treatment of Colon Cancer
por: Kong, Xianbin, et al.
Publicado: (2021)

Integrating network pharmacology, UPLC-Q–TOF–MS and molecular docking to investigate the effect and mechanism of Chuanxiong Renshen decoction against Alzheimer's disease
por: Shen, Zhuo Jun, et al.
Publicado: (2022)

Serum biomarkers of the calcium-deficient rats identified by metabolomics based on UPLC/Q-TOF MS/MS
por: Meng, Fanyu, et al.
Publicado: (2020)

Metabolomics Study of Different Germplasm Resources for Three Polygonatum Species Using UPLC-Q-TOF-MS/MS
por: Wang, Shiqiang, et al.
Publicado: (2022)

Identification of absorbed constituents and evaluation of the pharmacokinetics of main compounds after oral administration of yindanxinnaotong by UPLC-Q-TOF-MS and UPLC-QqQ-MS
por: Gong, Leilei, et al.
Publicado: (2018)

Profiling and Pharmacokinetic Studies of Alkaloids in Rats After Oral Administration of Zanthoxylum nitidum Decoction by UPLC-Q-TOF-MS/MS and HPLC-MS/MS
por: Huang, Aihua, et al.
Publicado: (2019)

Assessing the quality of Smilacis Glabrae Rhizoma (Tufuling) by colormetrics and UPLC-Q-TOF-MS
por: He, Xicheng, et al.
Publicado: (2016)

A UPLC-MS/MS application for comparisons of the hepatotoxicity of raw and processed Xanthii Fructus by energy metabolites
por: Jiang, Hai, et al.
Publicado: (2019)

UPLC-Q-TOF-MS Study of the Mechanism of THSWD for Breast Cancer Treatment
por: Duan, Xianchun, et al.
Publicado: (2020)

Chemical Profiling of Xueshuan Xinmaining Tablet by HPLC and UPLC-ESI-Q-TOF/MS
por: Han, Ya-Xin, et al.
Publicado: (2018)

Evaluation of Microbial Transformation of 10-deoxoartemisinin by UPLC-ESI-Q-TOF-MS(E)
por: Bai, Yue, et al.
Publicado: (2019)

UPLC-Q-TOF/MS Based Plasma Metabolomics for Identification of Paeonol’s Metabolic Target in Endometriosis
por: Liu, Jing, et al.
Publicado: (2023)

Identification of Components in Citri Sarcodactylis Fructus from Different Origins via UPLC-Q-Exactive Orbitrap/MS
por: Wang, Kanghui, et al.
Publicado: (2021)

Insight into the mechanisms of therapeutic hypothermia for asphyxia cardiac arrest using a comprehensive approach of GC-MS/MS and UPLC-Q-TOF-MS/MS based on serum metabolomics
por: Zhang, Yiyuan, et al.
Publicado: (2023)

Identification and Pharmacokinetic Studies on Complanatuside and Its Major Metabolites in Rats by UHPLC-Q-TOF-MS/MS and LC-MS/MS
por: Yao, Yu-Feng, et al.
Publicado: (2018)

Elucidating the material basis and potential mechanisms of Ershiwuwei Lvxue Pill acting on rheumatoid arthritis by UPLC-Q-TOF/MS and network pharmacology
por: Liu, Chuan, et al.
Publicado: (2022)

Sphingolipidomic Profiling of Rat Serum by UPLC-Q-TOF-MS: Application to Rheumatoid Arthritis Study
por: Qu, Fanghui, et al.
Publicado: (2018)

Qualitative and quantitative analyses of chemical components of Citri Sarcodactylis Fructus from different origins based on UPLC–Q–Exactive Orbitrap–MS and GC–MS
por: Ning, Jinrong, et al.
Publicado: (2022)

Plasma metabolic profiling analysis of Cortex Periplocae-induced cardiotoxicity based on UPLC/Q-TOF-MS
por: Li, Yubo, et al.
Publicado: (2018)

The Effect of Temperature on Pressurised Hot Water Extraction of Pharmacologically Important Metabolites as Analysed by UPLC-qTOF-MS and PCA
por: Khoza, B. S., et al.
Publicado: (2014)

Unveiling the Pharmacological Mechanisms of Eleutheroside E Against Postmenopausal Osteoporosis Through UPLC-Q/TOF-MS-Based Metabolomics
por: Ma, Yong-Sheng, et al.
Publicado: (2020)

Comprehensive metabolomics study on the pathogenesis of anaplastic astrocytoma via UPLC-Q/TOF-MS
por: Du, Chao, et al.
Publicado: (2022)

Systematically characterize the substance basis of Jinzhen oral liquid and their pharmacological mechanism using UPLC-Q-TOF/MS combined with network pharmacology analysis
por: Guo, Jing-Yan, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_9ek7r75mjd1amg64peu94v1a76