Neutralizing antibody 5-7 defines a distinct site of vulnerability in SARS-CoV-2 spike N-terminal domain

Antibodies that potently neutralize SARS-CoV-2 target mainly the receptor-binding domain or the N-terminal domain (NTD). Over a dozen potently neutralizing NTD-directed antibodies have been studied structurally, and all target a single antigenic supersite in NTD (site 1). Here, we report the cryo-EM...

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Detalles Bibliográficos
Autores principales: Cerutti, Gabriele, Guo, Yicheng, Wang, Pengfei, Nair, Manoj S., Wang, Maple, Huang, Yaoxing, Yu, Jian, Liu, Lihong, Katsamba, Phinikoula S., Bahna, Fabiana, Reddem, Eswar R., Kwong, Peter D., Ho, David D., Sheng, Zizhang, Shapiro, Lawrence
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Author(s). 2021
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519878/
https://www.ncbi.nlm.nih.gov/pubmed/34706271
http://dx.doi.org/10.1016/j.celrep.2021.109928

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519878/
https://www.ncbi.nlm.nih.gov/pubmed/34706271
http://dx.doi.org/10.1016/j.celrep.2021.109928

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