Cargando…

Sub-centrosomal mapping identifies augmin-γTuRC as part of a centriole-stabilizing scaffold

Centriole biogenesis and maintenance are crucial for cells to generate cilia and assemble centrosomes that function as microtubule organizing centers (MTOCs). Centriole biogenesis and MTOC function both require the microtubule nucleator γ-tubulin ring complex (γTuRC). It is widely accepted that γTuR...

Descripción completa

Detalles Bibliográficos
Autores principales:	Schweizer, Nina, Haren, Laurence, Dutto, Ilaria, Viais, Ricardo, Lacasa, Cristina, Merdes, Andreas, Lüders, Jens
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519919/ https://www.ncbi.nlm.nih.gov/pubmed/34654813 http://dx.doi.org/10.1038/s41467-021-26252-5

Ejemplares similares

Microtubule nucleation and γTuRC centrosome localization in interphase cells require ch-TOG
por: Ali, Aamir, et al.
Publicado: (2023)

The γTuRC Revisited: A Comparative Analysis of Interphase and Mitotic Human γTuRC Redefines the Set of Core Components and Identifies the Novel Subunit GCP8
por: Teixidó-Travesa, Neus, et al.
Publicado: (2010)

Drosophila melanogaster γ-TuRC is dispensable for targeting γ-tubulin to the centrosome and microtubule nucleation
por: Vérollet, Christel, et al.
Publicado: (2006)

γ-TuRC gives microtubules pause for thought
por: Short, Ben
Publicado: (2009)

γ-TuRC Heterogeneity Revealed by Analysis of Mozart1
por: Tovey, Corinne A., et al.
Publicado: (2018)

Modular assembly of the principal microtubule nucleator γ-TuRC
por: Würtz, Martin, et al.
Publicado: (2022)

Non-centrosomal nucleation mediated by augmin organizes microtubules in post-mitotic neurons and controls axonal microtubule polarity
por: Sánchez-Huertas, Carlos, et al.
Publicado: (2016)

TACC3–ch-TOG interaction regulates spindle microtubule assembly by controlling centrosomal recruitment of γ-TuRC
por: Rajeev, Resmi, et al.
Publicado: (2023)

Biochemical reconstitutions reveal principles of human γ-TuRC assembly and function
por: Wieczorek, Michal, et al.
Publicado: (2021)

Xgrip109: A γ Tubulin–Associated Protein with an Essential Role in γ Tubulin Ring Complex (γTuRC) Assembly and Centrosome Function
por: Martin, Ona C., et al.
Publicado: (1998)

The Nup107-160 complex and γ-TuRC regulate microtubule polymerization at kinetochores
por: Mishra, Ram Kumar, et al.
Publicado: (2010)

Ring closure activates yeast γTuRC for species-specific microtubule nucleation
por: Kollman, Justin M., et al.
Publicado: (2015)

Microtubule Organizing Centers Contain Testis-Specific γ-TuRC Proteins in Spermatids of Drosophila
por: Alzyoud, Elham, et al.
Publicado: (2021)

The transition state and regulation of γ-TuRC-mediated microtubule nucleation revealed by single molecule microscopy
por: Thawani, Akanksha, et al.
Publicado: (2020)

Kinesin-14 Pkl1 targets γ-tubulin for release from the γ-tubulin ring complex (γ-TuRC) ‬‬‬‬‬‬‬
por: Olmsted, Zachary T., et al.
Publicado: (2013)

The conserved centrosomin motif, γTuNA, forms a dimer that directly activates microtubule nucleation by the γ-tubulin ring complex (γTuRC)
por: Rale, Michael J, et al.
Publicado: (2022)

Kinesin-14 and kinesin-5 antagonistically regulate microtubule nucleation by γ-TuRC in yeast and human cells
por: Olmsted, Zachary T., et al.
Publicado: (2014)

The catalytic subunit of DNA polymerase δ inhibits γTuRC activity and regulates Golgi-derived microtubules
por: Shen, Yuehong, et al.
Publicado: (2017)

CRB3 navigates Rab11 trafficking vesicles to promote γTuRC assembly during ciliogenesis
por: Wang, Bo, et al.
Publicado: (2023)

The minus-end depolymerase KIF2A drives flux-like treadmilling of γTuRC-uncapped microtubules
por: Henkin, Gil, et al.
Publicado: (2023)

Augmin deficiency in neural stem cells causes p53-dependent apoptosis and aborts brain development
por: Viais, Ricardo, et al.
Publicado: (2021)

NEDD1-dependent recruitment of the γ-tubulin ring complex to the centrosome is necessary for centriole duplication and spindle assembly
por: Haren, Laurence, et al.
Publicado: (2006)

Dgp71WD is required for the assembly of the acentrosomal Meiosis I spindle, and is not a general targeting factor for the γ-TuRC
por: Reschen, Richard F., et al.
Publicado: (2012)

Microtubule Nucleation Properties of Single Human γTuRCs Explained by Their Cryo-EM Structure
por: Consolati, Tanja, et al.
Publicado: (2020)

Autoinhibition of Cnn binding to γ-TuRCs prevents ectopic microtubule nucleation and cell division defects
por: Tovey, Corinne A., et al.
Publicado: (2021)

Plk1-Dependent Recruitment of γ-Tubulin Complexes to Mitotic Centrosomes Involves Multiple PCM Components
por: Haren, Laurence, et al.
Publicado: (2009)

Augmin: a protein complex required for centrosome-independent microtubule generation within the spindle
por: Goshima, Gohta, et al.
Publicado: (2008)

Evolutionary problems in centrosome and centriole biology
por: Ross, L., et al.
Publicado: (2015)

Conserved Molecular Interactions in Centriole-to-Centrosome Conversion
por: Fu, Jingyan, et al.
Publicado: (2015)

Catching augmin in the act
por: Leslie, Mitch
Publicado: (2013)

PPP1R35 ensures centriole homeostasis by promoting centriole-to-centrosome conversion
por: Fong, Chii Shyang, et al.
Publicado: (2018)

The conversion of centrioles to centrosomes: essential coupling of duplication with segregation
por: Wang, Won-Jing, et al.
Publicado: (2011)

The Centrioles, Centrosomes, Basal Bodies, and Cilia of Drosophila melanogaster
por: Lattao, Ramona, et al.
Publicado: (2017)

Evolutionary conservation of centriole rotational asymmetry in the human centrosome
por: Gaudin, Noémie, et al.
Publicado: (2022)

The centrosome and cell proliferation
por: Srsen, Vlastimil, et al.
Publicado: (2006)

The centrosome protein NEDD1 as a potential pharmacological target to induce cell cycle arrest
por: Tillement, Vanessa, et al.
Publicado: (2009)

Augmin-ting the central spindle
por: Short, Ben
Publicado: (2010)

Molecular architecture of the augmin complex
por: Gabel, Clinton A., et al.
Publicado: (2022)

Mechanism of how augmin directly targets the γ-tubulin ring complex to microtubules
por: Song, Jae-Geun, et al.
Publicado: (2018)

CEP44 ensures the formation of bona fide centriole wall, a requirement for the centriole-to-centrosome conversion
por: Atorino, Enrico S., et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_1o11b5qslq2l2lcevabmait4el