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Empirically classifying network mechanisms
Network data are often explained by assuming a generating mechanism and estimating related parameters. Without a way to test the relevance of assumed mechanisms, conclusions from such models may be misleading. Here we introduce a simple empirical approach to mechanistically classify arbitrary networ...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519944/ https://www.ncbi.nlm.nih.gov/pubmed/34654854 http://dx.doi.org/10.1038/s41598-021-99251-7 |
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author | Langendorf, Ryan E. Burgess, Matthew G. |
author_facet | Langendorf, Ryan E. Burgess, Matthew G. |
author_sort | Langendorf, Ryan E. |
collection | PubMed |
description | Network data are often explained by assuming a generating mechanism and estimating related parameters. Without a way to test the relevance of assumed mechanisms, conclusions from such models may be misleading. Here we introduce a simple empirical approach to mechanistically classify arbitrary network data as originating from any of a set of candidate mechanisms or none of them. We tested our approach on simulated data from five of the most widely studied network mechanisms, and found it to be highly accurate. We then tested 1284 empirical networks spanning 17 different kinds of systems against these five widely studied mechanisms. We found that 387 (30%) of these empirical networks were classified as unlike any of the mechanisms, and only 1% or fewer of the networks classified as each of the mechanisms for which our approach was most sensitive. Based on this, we use Bayes’ theorem to show that most of the 70% of empirical networks our approach classified as a mechanism could be false positives, because of the high sensitivity required of a test to detect rarely occurring mechanisms. Thus, it is possible that very few of our empirical networks are described by any of these five widely studied mechanisms. Additionally, 93 networks (7%) were classified as plausibly being governed by each of multiple mechanisms. This raises the possibility that some systems are governed by mixtures of mechanisms. We show that mixtures are often unidentifiable because different mixtures can produce structurally equivalent networks, but that we can still accurately predict out-of-sample functional properties. |
format | Online Article Text |
id | pubmed-8519944 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-85199442021-10-20 Empirically classifying network mechanisms Langendorf, Ryan E. Burgess, Matthew G. Sci Rep Article Network data are often explained by assuming a generating mechanism and estimating related parameters. Without a way to test the relevance of assumed mechanisms, conclusions from such models may be misleading. Here we introduce a simple empirical approach to mechanistically classify arbitrary network data as originating from any of a set of candidate mechanisms or none of them. We tested our approach on simulated data from five of the most widely studied network mechanisms, and found it to be highly accurate. We then tested 1284 empirical networks spanning 17 different kinds of systems against these five widely studied mechanisms. We found that 387 (30%) of these empirical networks were classified as unlike any of the mechanisms, and only 1% or fewer of the networks classified as each of the mechanisms for which our approach was most sensitive. Based on this, we use Bayes’ theorem to show that most of the 70% of empirical networks our approach classified as a mechanism could be false positives, because of the high sensitivity required of a test to detect rarely occurring mechanisms. Thus, it is possible that very few of our empirical networks are described by any of these five widely studied mechanisms. Additionally, 93 networks (7%) were classified as plausibly being governed by each of multiple mechanisms. This raises the possibility that some systems are governed by mixtures of mechanisms. We show that mixtures are often unidentifiable because different mixtures can produce structurally equivalent networks, but that we can still accurately predict out-of-sample functional properties. Nature Publishing Group UK 2021-10-15 /pmc/articles/PMC8519944/ /pubmed/34654854 http://dx.doi.org/10.1038/s41598-021-99251-7 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Langendorf, Ryan E. Burgess, Matthew G. Empirically classifying network mechanisms |
title | Empirically classifying network mechanisms |
title_full | Empirically classifying network mechanisms |
title_fullStr | Empirically classifying network mechanisms |
title_full_unstemmed | Empirically classifying network mechanisms |
title_short | Empirically classifying network mechanisms |
title_sort | empirically classifying network mechanisms |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519944/ https://www.ncbi.nlm.nih.gov/pubmed/34654854 http://dx.doi.org/10.1038/s41598-021-99251-7 |
work_keys_str_mv | AT langendorfryane empiricallyclassifyingnetworkmechanisms AT burgessmatthewg empiricallyclassifyingnetworkmechanisms |