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Deep post-GWAS analysis identifies potential risk genes and risk variants for Alzheimer’s disease, providing new insights into its disease mechanisms

Alzheimer’s disease (AD) is a genetically complex, multifactorial neurodegenerative disease. It affects more than 45 million people worldwide and currently remains untreatable. Although genome-wide association studies (GWAS) have identified many AD-associated common variants, only about 25 genes are...

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Detalles Bibliográficos
Autores principales:	Wang, Zhen, Zhang, Quanwei, Lin, Jhih-Rong, Jabalameli, M. Reza, Mitra, Joydeep, Nguyen, Nha, Zhang, Zhengdong D.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519945/ https://www.ncbi.nlm.nih.gov/pubmed/34654853 http://dx.doi.org/10.1038/s41598-021-99352-3

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