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Long-term stability predictions of therapeutic monoclonal antibodies in solution using Arrhenius-based kinetics
Long-term stability of monoclonal antibodies to be used as biologics is a key aspect in their development. Therefore, its possible early prediction from accelerated stability studies is of major interest, despite currently being regarded as not sufficiently robust. In this work, using a combination...
Autores principales: | Kuzman, Drago, Bunc, Marko, Ravnik, Miha, Reiter, Fritz, Žagar, Lan, Bončina, Matjaž |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519954/ https://www.ncbi.nlm.nih.gov/pubmed/34654882 http://dx.doi.org/10.1038/s41598-021-99875-9 |
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