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Podocyte-specific Crb2 knockout mice develop focal segmental glomerulosclerosis

Crb2 is a cell polarity-related type I transmembrane protein expressed in the apical membrane of podocytes. Knockdown of crb2 causes glomerular permeability defects in zebrafish, and its complete knockout causes embryonic lethality in mice. There are also reports of Crb2 mutations in patients with s...

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Detalles Bibliográficos
Autores principales:	Tanoue, Akiko, Katayama, Kan, Ito, Yugo, Joh, Kensuke, Toda, Masaaki, Yasuma, Taro, D’Alessandro-Gabazza, Corina N., Kawachi, Hiroshi, Yan, Kunimasa, Ito, Masaaki, Gabazza, Esteban C., Tryggvason, Karl, Dohi, Kaoru
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519956/ https://www.ncbi.nlm.nih.gov/pubmed/34654837 http://dx.doi.org/10.1038/s41598-021-00159-z

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