siRNA delivery using intelligent chitosan-capped mesoporous silica nanoparticles for overcoming multidrug resistance in malignant carcinoma cells

Although siRNA is a promising technology for cancer gene therapy, effective cytoplasmic delivery has remained a significant challenge. In this paper, a potent siRNA transfer system with active targeting moieties toward cancer cells and a high loading capacity is introduced to inhibit drug resistance...

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Detalles Bibliográficos
Autores principales: Heidari, Razieh, Khosravian, Pegah, Mirzaei, Seyed Abbas, Elahian, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519957/
https://www.ncbi.nlm.nih.gov/pubmed/34654836
http://dx.doi.org/10.1038/s41598-021-00085-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519957/
https://www.ncbi.nlm.nih.gov/pubmed/34654836
http://dx.doi.org/10.1038/s41598-021-00085-0

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