Systematic phenotyping and characterization of the 5xFAD mouse model of Alzheimer’s disease

Mouse models of human diseases are invaluable tools for studying pathogenic mechanisms and testing interventions and therapeutics. For disorders such as Alzheimer’s disease in which numerous models are being generated, a challenging first step is to identify the most appropriate model and age to eff...

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Detalles Bibliográficos
Autores principales: Forner, Stefania, Kawauchi, Shimako, Balderrama-Gutierrez, Gabriela, Kramár, Enikö A., Matheos, Dina P., Phan, Jimmy, Javonillo, Dominic I., Tran, Kristine M., Hingco, Edna, da Cunha, Celia, Rezaie, Narges, Alcantara, Joshua A., Baglietto-Vargas, David, Jansen, Camden, Neumann, Jonathan, Wood, Marcelo A., MacGregor, Grant R., Mortazavi, Ali, Tenner, Andrea J., LaFerla, Frank M., Green, Kim N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Data Descriptor
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8519958/
https://www.ncbi.nlm.nih.gov/pubmed/34654824
http://dx.doi.org/10.1038/s41597-021-01054-y

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