Investigation of serum β-defensin-1 level in calves with coccidiosis

OBJECTIVE: Coccidiosis is a protozoan infection that can result in hemorrhagic diarrhea, depression, weakness, weight loss, and even mortality in young animals. β-defensin-1 is an antimicrobial peptide produced largely by epithelial cells in the skin and mucosa. It possesses antifungal, antibacteria...

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Autor principal: Koçhan, Akın
Formato: Online Artículo Texto
Lenguaje:English
Publicado: A periodical of the Network for the Veterinarians of Bangladesh (BDvetNET) 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520148/
https://www.ncbi.nlm.nih.gov/pubmed/34722749
http://dx.doi.org/10.5455/javar.2021.h539
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author Koçhan, Akın
author_facet Koçhan, Akın
author_sort Koçhan, Akın
collection PubMed
description OBJECTIVE: Coccidiosis is a protozoan infection that can result in hemorrhagic diarrhea, depression, weakness, weight loss, and even mortality in young animals. β-defensin-1 is an antimicrobial peptide produced largely by epithelial cells in the skin and mucosa. It possesses antifungal, antibacterial, antiparasitic, and antiviral properties. The goal of this study was to evaluate how β-defensin-1 levels changed in coccidiosis-infected calves. MATERIALS AND METHODS: The sample included 10 coccidiosis-positive calves and 7 healthy calves, for a total of 17 calves of diverse breeds and older than 15 days. To assess the level of β-defensin-1, blood samples were obtained from the vena jugularis of the animals. The concentrations of β-defensin-1 in the serum were measured using a commercial ELISA kit. RESULTS: Although the serum β-defensin-1 level decreased in infected animals, the drop was not statistically significant when compared to the control group. CONCLUSION: According to the study’s findings, there was no significant change in the serum β-defensin-1 level in coccidiosis-infected calves. We believe that it will be advantageous to conduct additional studies with a larger sample size in order to acquire more precise results.
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spelling pubmed-85201482021-10-28 Investigation of serum β-defensin-1 level in calves with coccidiosis Koçhan, Akın J Adv Vet Anim Res Original Article OBJECTIVE: Coccidiosis is a protozoan infection that can result in hemorrhagic diarrhea, depression, weakness, weight loss, and even mortality in young animals. β-defensin-1 is an antimicrobial peptide produced largely by epithelial cells in the skin and mucosa. It possesses antifungal, antibacterial, antiparasitic, and antiviral properties. The goal of this study was to evaluate how β-defensin-1 levels changed in coccidiosis-infected calves. MATERIALS AND METHODS: The sample included 10 coccidiosis-positive calves and 7 healthy calves, for a total of 17 calves of diverse breeds and older than 15 days. To assess the level of β-defensin-1, blood samples were obtained from the vena jugularis of the animals. The concentrations of β-defensin-1 in the serum were measured using a commercial ELISA kit. RESULTS: Although the serum β-defensin-1 level decreased in infected animals, the drop was not statistically significant when compared to the control group. CONCLUSION: According to the study’s findings, there was no significant change in the serum β-defensin-1 level in coccidiosis-infected calves. We believe that it will be advantageous to conduct additional studies with a larger sample size in order to acquire more precise results. A periodical of the Network for the Veterinarians of Bangladesh (BDvetNET) 2021-09-20 /pmc/articles/PMC8520148/ /pubmed/34722749 http://dx.doi.org/10.5455/javar.2021.h539 Text en Copyright: © Journal of Advanced Veterinary and Animal Research https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) )
spellingShingle Original Article
Koçhan, Akın
Investigation of serum β-defensin-1 level in calves with coccidiosis
title Investigation of serum β-defensin-1 level in calves with coccidiosis
title_full Investigation of serum β-defensin-1 level in calves with coccidiosis
title_fullStr Investigation of serum β-defensin-1 level in calves with coccidiosis
title_full_unstemmed Investigation of serum β-defensin-1 level in calves with coccidiosis
title_short Investigation of serum β-defensin-1 level in calves with coccidiosis
title_sort investigation of serum β-defensin-1 level in calves with coccidiosis
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520148/
https://www.ncbi.nlm.nih.gov/pubmed/34722749
http://dx.doi.org/10.5455/javar.2021.h539
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