Investigation of serum β-defensin-1 level in calves with coccidiosis
OBJECTIVE: Coccidiosis is a protozoan infection that can result in hemorrhagic diarrhea, depression, weakness, weight loss, and even mortality in young animals. β-defensin-1 is an antimicrobial peptide produced largely by epithelial cells in the skin and mucosa. It possesses antifungal, antibacteria...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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A periodical of the Network for the Veterinarians of Bangladesh (BDvetNET)
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520148/ https://www.ncbi.nlm.nih.gov/pubmed/34722749 http://dx.doi.org/10.5455/javar.2021.h539 |
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author | Koçhan, Akın |
author_facet | Koçhan, Akın |
author_sort | Koçhan, Akın |
collection | PubMed |
description | OBJECTIVE: Coccidiosis is a protozoan infection that can result in hemorrhagic diarrhea, depression, weakness, weight loss, and even mortality in young animals. β-defensin-1 is an antimicrobial peptide produced largely by epithelial cells in the skin and mucosa. It possesses antifungal, antibacterial, antiparasitic, and antiviral properties. The goal of this study was to evaluate how β-defensin-1 levels changed in coccidiosis-infected calves. MATERIALS AND METHODS: The sample included 10 coccidiosis-positive calves and 7 healthy calves, for a total of 17 calves of diverse breeds and older than 15 days. To assess the level of β-defensin-1, blood samples were obtained from the vena jugularis of the animals. The concentrations of β-defensin-1 in the serum were measured using a commercial ELISA kit. RESULTS: Although the serum β-defensin-1 level decreased in infected animals, the drop was not statistically significant when compared to the control group. CONCLUSION: According to the study’s findings, there was no significant change in the serum β-defensin-1 level in coccidiosis-infected calves. We believe that it will be advantageous to conduct additional studies with a larger sample size in order to acquire more precise results. |
format | Online Article Text |
id | pubmed-8520148 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | A periodical of the Network for the Veterinarians of Bangladesh (BDvetNET) |
record_format | MEDLINE/PubMed |
spelling | pubmed-85201482021-10-28 Investigation of serum β-defensin-1 level in calves with coccidiosis Koçhan, Akın J Adv Vet Anim Res Original Article OBJECTIVE: Coccidiosis is a protozoan infection that can result in hemorrhagic diarrhea, depression, weakness, weight loss, and even mortality in young animals. β-defensin-1 is an antimicrobial peptide produced largely by epithelial cells in the skin and mucosa. It possesses antifungal, antibacterial, antiparasitic, and antiviral properties. The goal of this study was to evaluate how β-defensin-1 levels changed in coccidiosis-infected calves. MATERIALS AND METHODS: The sample included 10 coccidiosis-positive calves and 7 healthy calves, for a total of 17 calves of diverse breeds and older than 15 days. To assess the level of β-defensin-1, blood samples were obtained from the vena jugularis of the animals. The concentrations of β-defensin-1 in the serum were measured using a commercial ELISA kit. RESULTS: Although the serum β-defensin-1 level decreased in infected animals, the drop was not statistically significant when compared to the control group. CONCLUSION: According to the study’s findings, there was no significant change in the serum β-defensin-1 level in coccidiosis-infected calves. We believe that it will be advantageous to conduct additional studies with a larger sample size in order to acquire more precise results. A periodical of the Network for the Veterinarians of Bangladesh (BDvetNET) 2021-09-20 /pmc/articles/PMC8520148/ /pubmed/34722749 http://dx.doi.org/10.5455/javar.2021.h539 Text en Copyright: © Journal of Advanced Veterinary and Animal Research https://creativecommons.org/licenses/by/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution 4.0 License (http://creativecommons.org/licenses/by/4.0 (https://creativecommons.org/licenses/by/4.0/) ) |
spellingShingle | Original Article Koçhan, Akın Investigation of serum β-defensin-1 level in calves with coccidiosis |
title | Investigation of serum β-defensin-1 level in calves with coccidiosis |
title_full | Investigation of serum β-defensin-1 level in calves with coccidiosis |
title_fullStr | Investigation of serum β-defensin-1 level in calves with coccidiosis |
title_full_unstemmed | Investigation of serum β-defensin-1 level in calves with coccidiosis |
title_short | Investigation of serum β-defensin-1 level in calves with coccidiosis |
title_sort | investigation of serum β-defensin-1 level in calves with coccidiosis |
topic | Original Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520148/ https://www.ncbi.nlm.nih.gov/pubmed/34722749 http://dx.doi.org/10.5455/javar.2021.h539 |
work_keys_str_mv | AT kochanakın investigationofserumbdefensin1levelincalveswithcoccidiosis |