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Surgical removal of a telemetry system in a cynomolgus monkey (Macaca fascicularis): a 12-month observation study
BACKGROUND: Telemetry is a wireless implanted device that measures biological signals in conscious animals and usually requires surgery for its removal when the study is finished. After removing the device, the animals are either used for other studies or euthanatized. CASE PRESENTATION: Herein, we...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520245/ https://www.ncbi.nlm.nih.gov/pubmed/34656182 http://dx.doi.org/10.1186/s42826-021-00106-z |
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author | Cho, Doo-Wan Han, Hyoung-Yun Yang, Mi-Jin Woo, Dong Ho Han, Su-Cheol Yang, Young-Su |
author_facet | Cho, Doo-Wan Han, Hyoung-Yun Yang, Mi-Jin Woo, Dong Ho Han, Su-Cheol Yang, Young-Su |
author_sort | Cho, Doo-Wan |
collection | PubMed |
description | BACKGROUND: Telemetry is a wireless implanted device that measures biological signals in conscious animals and usually requires surgery for its removal when the study is finished. After removing the device, the animals are either used for other studies or euthanatized. CASE PRESENTATION: Herein, we report the case of a living cynomolgus monkey (Macaca fascicularis) that was used for the entire experimental period, instead of euthanasia, after surgical removal of an implanted telemetry system. Radiography was used to determine the status of the implanted telemetry, following which, a repair surgery was performed for removing the system; clinical signs were used to preserve the life of the cynomolgus monkey. Postoperative clinical signs, food consumption, hematology, and serum biochemistry were examined during the 12-month observational period. No abnormal readings or conditions were observed in the subject after implant removal. CONCLUSIONS: This study may be a useful case report for living cynomolgus monkeys in telemetry implantations used throughout the study period. We suggest minimizing the suffering and improving the welfare of these animals. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s42826-021-00106-z. |
format | Online Article Text |
id | pubmed-8520245 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | BioMed Central |
record_format | MEDLINE/PubMed |
spelling | pubmed-85202452021-10-20 Surgical removal of a telemetry system in a cynomolgus monkey (Macaca fascicularis): a 12-month observation study Cho, Doo-Wan Han, Hyoung-Yun Yang, Mi-Jin Woo, Dong Ho Han, Su-Cheol Yang, Young-Su Lab Anim Res Case Report BACKGROUND: Telemetry is a wireless implanted device that measures biological signals in conscious animals and usually requires surgery for its removal when the study is finished. After removing the device, the animals are either used for other studies or euthanatized. CASE PRESENTATION: Herein, we report the case of a living cynomolgus monkey (Macaca fascicularis) that was used for the entire experimental period, instead of euthanasia, after surgical removal of an implanted telemetry system. Radiography was used to determine the status of the implanted telemetry, following which, a repair surgery was performed for removing the system; clinical signs were used to preserve the life of the cynomolgus monkey. Postoperative clinical signs, food consumption, hematology, and serum biochemistry were examined during the 12-month observational period. No abnormal readings or conditions were observed in the subject after implant removal. CONCLUSIONS: This study may be a useful case report for living cynomolgus monkeys in telemetry implantations used throughout the study period. We suggest minimizing the suffering and improving the welfare of these animals. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1186/s42826-021-00106-z. BioMed Central 2021-10-16 /pmc/articles/PMC8520245/ /pubmed/34656182 http://dx.doi.org/10.1186/s42826-021-00106-z Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data. |
spellingShingle | Case Report Cho, Doo-Wan Han, Hyoung-Yun Yang, Mi-Jin Woo, Dong Ho Han, Su-Cheol Yang, Young-Su Surgical removal of a telemetry system in a cynomolgus monkey (Macaca fascicularis): a 12-month observation study |
title | Surgical removal of a telemetry system in a cynomolgus monkey (Macaca fascicularis): a 12-month observation study |
title_full | Surgical removal of a telemetry system in a cynomolgus monkey (Macaca fascicularis): a 12-month observation study |
title_fullStr | Surgical removal of a telemetry system in a cynomolgus monkey (Macaca fascicularis): a 12-month observation study |
title_full_unstemmed | Surgical removal of a telemetry system in a cynomolgus monkey (Macaca fascicularis): a 12-month observation study |
title_short | Surgical removal of a telemetry system in a cynomolgus monkey (Macaca fascicularis): a 12-month observation study |
title_sort | surgical removal of a telemetry system in a cynomolgus monkey (macaca fascicularis): a 12-month observation study |
topic | Case Report |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520245/ https://www.ncbi.nlm.nih.gov/pubmed/34656182 http://dx.doi.org/10.1186/s42826-021-00106-z |
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