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Employing multiple synchronous outcome samples per subject to improve study efficiency
BACKGROUND: Accuracy can be improved by taking multiple synchronous samples from each subject in a study to estimate the endpoint of interest if sample values are not highly correlated. If feasible, it is useful to assess the value of this cluster approach when planning studies. Multiple assessments...
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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BioMed Central
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520627/ https://www.ncbi.nlm.nih.gov/pubmed/34657591 http://dx.doi.org/10.1186/s12874-021-01414-7 |