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Are morbidity and mortality estimates from randomized controlled trials externally valid? A comparison of outcomes among infants enrolled into an RCT or a cohort study in Botswana

BACKGROUND: The external validity of the randomized controlled trial (RCT) refers to the extent to which the results of the RCT apply to the relevant, non-trial population and is impacted by its eligibility criteria, its organization, and its delivery of the intervention. Here, we compared the outco...

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Detalles Bibliográficos
Autores principales: Thivalapill, Neil, Lockman, Shahin, Powis, Kathleen, Zash, Rebecca, Leidner, Jean, Ajibola, Gbolahan, Mmalane, Mompati, Makhema, Joseph, Shapiro, Roger L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520637/
https://www.ncbi.nlm.nih.gov/pubmed/34657589
http://dx.doi.org/10.1186/s12874-021-01343-5