Cargando…
Type I Interferon signaling controls the accumulation and transcriptomes of monocytes in the aged lung
Aging is paradoxically associated with a deteriorated immune defense (immunosenescence) and increased basal levels of tissue inflammation (inflammaging). The lung is particularly sensitive to the effects of aging. The immune cell mechanisms underlying physiological lung aging remain poorly understoo...
Autores principales: | D’Souza, Shanti S., Zhang, Yuanyue, Bailey, Jacob T., Fung, Ivan T. H., Kuentzel, Marcy L., Chittur, Sridar V., Yang, Qi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520712/ https://www.ncbi.nlm.nih.gov/pubmed/34547174 http://dx.doi.org/10.1111/acel.13470 |
Ejemplares similares
-
Group 2 innate lymphoid cells are numerically and functionally deficient in the triple transgenic mouse model of Alzheimer’s disease
por: Fung, Ivan Ting Hin, et al.
Publicado: (2021) -
Compartmentalized effects of aging on group 2 innate lymphoid cell development and function
por: D'Souza, Shanti S., et al.
Publicado: (2019) -
Activation of group 2 innate lymphoid cells alleviates aging-associated cognitive decline
por: Fung, Ivan Ting Hin, et al.
Publicado: (2020) -
Monocyte and Macrophage Lipid Accumulation Results in Down-Regulated Type-I Interferon Responses
por: Willemsen, Lisa, et al.
Publicado: (2022) -
Commentary: Monocyte and macrophage lipid accumulation results in down-regulated type-I interferon responses
por: Li, Fang, et al.
Publicado: (2023)