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Late‐in‐life treadmill training rejuvenates autophagy, protein aggregate clearance, and function in mouse hearts
Protein quality control mechanisms decline during the process of cardiac aging. This enables the accumulation of protein aggregates and damaged organelles that contribute to age‐associated cardiac dysfunction. Macroautophagy is the process by which post‐mitotic cells such as cardiomyocytes clear def...
Autores principales: | Cho, Jae Min, Park, Seul‐Ki, Ghosh, Rajeshwary, Ly, Kellsey, Ramous, Caroline, Thompson, Lauren, Hansen, Michele, Mattera, Maria Sara de Lima Coutinho, Pires, Karla Maria, Ferhat, Maroua, Mookherjee, Sohom, Whitehead, Kevin J., Carter, Kandis, Buffolo, Márcio, Boudina, Sihem, Symons, J. David |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520717/ https://www.ncbi.nlm.nih.gov/pubmed/34554626 http://dx.doi.org/10.1111/acel.13467 |
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