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Direct observation of aggregate-triggered selective autophagy in human cells

Degradation of aggregates by selective autophagy is important as damaged proteins may impose a threat to cellular homeostasis. Although the core components of the autophagy machinery are well characterized, the spatiotemporal regulation of many selective autophagy processes, including aggrephagy, re...

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Detalles Bibliográficos
Autores principales: Janssen, Anne F. J., Korsten, Giel, Nijenhuis, Wilco, Katrukha, Eugene A., Kapitein, Lukas C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists Ltd 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520732/
https://www.ncbi.nlm.nih.gov/pubmed/34447998
http://dx.doi.org/10.1242/jcs.258824

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