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RAMPART: A phase III multi-arm multi-stage trial of adjuvant checkpoint inhibitors in patients with resected primary renal cell carcinoma (RCC) at high or intermediate risk of relapse
BACKGROUND: 20–60% of patients with initially locally advanced Renal Cell Carcinoma (RCC) develop metastatic disease despite optimal surgical excision. Adjuvant strategies have been tested in RCC including cytokines, radiotherapy, hormones and oral tyrosine-kinase inhibitors (TKIs), with limited suc...
Autores principales: | Oza, Bhavna, Frangou, Eleni, Smith, Ben, Bryant, Hanna, Kaplan, Rick, Choodari-Oskooei, Babak, Powles, Tom, Stewart, Grant D., Albiges, Laurence, Bex, Axel, Choueiri, Toni K., Davis, Ian D., Eisen, Tim, Fielding, Alison, Harrison, David, McWhirter, Anita, Mulhere, Salena, Nathan, Paul, Rini, Brian, Ritchie, Alastair, Scovell, Sarah, Shakeshaft, Clare, Stockler, Martin R., Thorogood, Nat, Parmar, Mahesh K.B., Larkin, James, Meade, Angela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520913/ https://www.ncbi.nlm.nih.gov/pubmed/34538402 http://dx.doi.org/10.1016/j.cct.2021.106482 |
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