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Chimney Graft Technique Combined With Embolization for Treating Ruptured Aortic Arch Lesions

Background: This study aimed to share the experience in applying the chimney graft technique combined with embolization for treating aortic arch rupture under emergency conditions and evaluating early-term results in these patients. Methods: This study retrospectively included patients with ruptured...

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Autores principales: Bao, Xianhao, Zhao, Yuxi, Li, Tao, Wu, Mingwei, Zeng, Zhaoxiang, Gao, Minxin, Xu, Ding, Feng, Jiaxuan, Feng, Rui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520930/
https://www.ncbi.nlm.nih.gov/pubmed/34671650
http://dx.doi.org/10.3389/fcvm.2021.711283
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author Bao, Xianhao
Zhao, Yuxi
Li, Tao
Wu, Mingwei
Zeng, Zhaoxiang
Gao, Minxin
Xu, Ding
Feng, Jiaxuan
Feng, Rui
author_facet Bao, Xianhao
Zhao, Yuxi
Li, Tao
Wu, Mingwei
Zeng, Zhaoxiang
Gao, Minxin
Xu, Ding
Feng, Jiaxuan
Feng, Rui
author_sort Bao, Xianhao
collection PubMed
description Background: This study aimed to share the experience in applying the chimney graft technique combined with embolization for treating aortic arch rupture under emergency conditions and evaluating early-term results in these patients. Methods: This study retrospectively included patients with ruptured aortic arch lesions who received the chimney graft technique combined with embolization between March 2016 and March 2021. The primary endpoint was a technical success, deemed as successful stent graft deployment to the planned location, patency of the target branch vessel, and absence of significant type I endoleak. The secondary endpoint was clinical success defined with the size of false lumen in follow-up remaining unchanged or decreasing over time, 30-day mortality, complication, and primary patency of chimney graft. Results: This study included 12 patients (age, 61 ± 12 years; male, 83%). Five patients (42%) received single chimney, one patient (8%) received double chimney, and six patients (50%) received triple chimney. Intraoperative type I endoleak occurred in six patients (50%) who underwent endovascular embolization in the primary operation. Post-operative type I endoleak, evaluated by computed tomography angiography examination following the primary operation, occurred in seven patients (58%), including one patient who received endovascular embolization two times. All patients with post-operative type I endoleak were successfully re-treated using coil and Onyx glue within 1 week, and the median length of stay was 22 ± 11 days (range: 7–44 days). Overall technical success was 100%. Eleven patients had completed their follow-up (median, 12 months, range: 1–34 months), and one patient was out of contact. The 30-day mortality was 9% (1/11, post-operative death of a patient with cerebral hemorrhage). No major complications and no chimney compression, migration, occlusion, or stenosis were recorded during follow-up. Seven patients (58%) have ≥6 months of clinical follow-up time with appropriate imaging. In four (57%) of these patients, diameter stabilization was detected, whereas three (43%) experienced significant reduction (≥5 mm). Conclusion: The patients in this study had satisfactory early-term outcomes. The chimney graft technique combined with coil and Onyx glue embolization may be a safe and effective treatment for ruptured aortic arch lesions under emergency conditions.
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spelling pubmed-85209302021-10-19 Chimney Graft Technique Combined With Embolization for Treating Ruptured Aortic Arch Lesions Bao, Xianhao Zhao, Yuxi Li, Tao Wu, Mingwei Zeng, Zhaoxiang Gao, Minxin Xu, Ding Feng, Jiaxuan Feng, Rui Front Cardiovasc Med Cardiovascular Medicine Background: This study aimed to share the experience in applying the chimney graft technique combined with embolization for treating aortic arch rupture under emergency conditions and evaluating early-term results in these patients. Methods: This study retrospectively included patients with ruptured aortic arch lesions who received the chimney graft technique combined with embolization between March 2016 and March 2021. The primary endpoint was a technical success, deemed as successful stent graft deployment to the planned location, patency of the target branch vessel, and absence of significant type I endoleak. The secondary endpoint was clinical success defined with the size of false lumen in follow-up remaining unchanged or decreasing over time, 30-day mortality, complication, and primary patency of chimney graft. Results: This study included 12 patients (age, 61 ± 12 years; male, 83%). Five patients (42%) received single chimney, one patient (8%) received double chimney, and six patients (50%) received triple chimney. Intraoperative type I endoleak occurred in six patients (50%) who underwent endovascular embolization in the primary operation. Post-operative type I endoleak, evaluated by computed tomography angiography examination following the primary operation, occurred in seven patients (58%), including one patient who received endovascular embolization two times. All patients with post-operative type I endoleak were successfully re-treated using coil and Onyx glue within 1 week, and the median length of stay was 22 ± 11 days (range: 7–44 days). Overall technical success was 100%. Eleven patients had completed their follow-up (median, 12 months, range: 1–34 months), and one patient was out of contact. The 30-day mortality was 9% (1/11, post-operative death of a patient with cerebral hemorrhage). No major complications and no chimney compression, migration, occlusion, or stenosis were recorded during follow-up. Seven patients (58%) have ≥6 months of clinical follow-up time with appropriate imaging. In four (57%) of these patients, diameter stabilization was detected, whereas three (43%) experienced significant reduction (≥5 mm). Conclusion: The patients in this study had satisfactory early-term outcomes. The chimney graft technique combined with coil and Onyx glue embolization may be a safe and effective treatment for ruptured aortic arch lesions under emergency conditions. Frontiers Media S.A. 2021-10-04 /pmc/articles/PMC8520930/ /pubmed/34671650 http://dx.doi.org/10.3389/fcvm.2021.711283 Text en Copyright © 2021 Bao, Zhao, Li, Wu, Zeng, Gao, Xu, Feng and Feng. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Bao, Xianhao
Zhao, Yuxi
Li, Tao
Wu, Mingwei
Zeng, Zhaoxiang
Gao, Minxin
Xu, Ding
Feng, Jiaxuan
Feng, Rui
Chimney Graft Technique Combined With Embolization for Treating Ruptured Aortic Arch Lesions
title Chimney Graft Technique Combined With Embolization for Treating Ruptured Aortic Arch Lesions
title_full Chimney Graft Technique Combined With Embolization for Treating Ruptured Aortic Arch Lesions
title_fullStr Chimney Graft Technique Combined With Embolization for Treating Ruptured Aortic Arch Lesions
title_full_unstemmed Chimney Graft Technique Combined With Embolization for Treating Ruptured Aortic Arch Lesions
title_short Chimney Graft Technique Combined With Embolization for Treating Ruptured Aortic Arch Lesions
title_sort chimney graft technique combined with embolization for treating ruptured aortic arch lesions
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520930/
https://www.ncbi.nlm.nih.gov/pubmed/34671650
http://dx.doi.org/10.3389/fcvm.2021.711283
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