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Pulmonary Artery Stump Thrombosis: To Treat or Not to Treat? The Question Is Still Open. Description of a Case and Review of the Literature

Pulmonary artery stump thrombosis (PAST) represents a possible complication after lung surgery. We report the case of a 59-year-old man who presented with dyspnoea about 4 years after right pneumonectomy due to squamous cell lung cancer. A CT-scan showed the presence of pulmonary artery stump thromb...

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Autores principales: Mirijello, Antonio, Santoliquido, Mariateresa, Piscitelli, Pamela, Borelli, Cristina, Serviddio, Gaetano, Simeone, Anna, Grandone, Elvira, De Cosmo, Salvatore
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520941/
https://www.ncbi.nlm.nih.gov/pubmed/34671651
http://dx.doi.org/10.3389/fcvm.2021.714826
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author Mirijello, Antonio
Santoliquido, Mariateresa
Piscitelli, Pamela
Borelli, Cristina
Serviddio, Gaetano
Simeone, Anna
Grandone, Elvira
De Cosmo, Salvatore
author_facet Mirijello, Antonio
Santoliquido, Mariateresa
Piscitelli, Pamela
Borelli, Cristina
Serviddio, Gaetano
Simeone, Anna
Grandone, Elvira
De Cosmo, Salvatore
author_sort Mirijello, Antonio
collection PubMed
description Pulmonary artery stump thrombosis (PAST) represents a possible complication after lung surgery. We report the case of a 59-year-old man who presented with dyspnoea about 4 years after right pneumonectomy due to squamous cell lung cancer. A CT-scan showed the presence of pulmonary artery stump thrombosis. Although there was no evidence of pulmonary embolism, given the clinical features and radiological shape of the thrombus, anticoagulation treatment with low-molecular-weight heparin was started with improvement of symptoms. The patient was discharged on anticoagulant treatment and a pulmonary CT-scan performed 4 months later showed an almost complete resolution of the PAST. Pathophysiological mechanisms of PAST are still unknown, although several hypotheses have been proposed. However, the decision to treat PAST with anticoagulants is still controversial. A review of literature will be provided in order to discuss risk factors, possible etiologies and to highlight clinical and radiological characteristics that could suggest to treat this condition, in particular when there is an increased risk of complications.
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spelling pubmed-85209412021-10-19 Pulmonary Artery Stump Thrombosis: To Treat or Not to Treat? The Question Is Still Open. Description of a Case and Review of the Literature Mirijello, Antonio Santoliquido, Mariateresa Piscitelli, Pamela Borelli, Cristina Serviddio, Gaetano Simeone, Anna Grandone, Elvira De Cosmo, Salvatore Front Cardiovasc Med Cardiovascular Medicine Pulmonary artery stump thrombosis (PAST) represents a possible complication after lung surgery. We report the case of a 59-year-old man who presented with dyspnoea about 4 years after right pneumonectomy due to squamous cell lung cancer. A CT-scan showed the presence of pulmonary artery stump thrombosis. Although there was no evidence of pulmonary embolism, given the clinical features and radiological shape of the thrombus, anticoagulation treatment with low-molecular-weight heparin was started with improvement of symptoms. The patient was discharged on anticoagulant treatment and a pulmonary CT-scan performed 4 months later showed an almost complete resolution of the PAST. Pathophysiological mechanisms of PAST are still unknown, although several hypotheses have been proposed. However, the decision to treat PAST with anticoagulants is still controversial. A review of literature will be provided in order to discuss risk factors, possible etiologies and to highlight clinical and radiological characteristics that could suggest to treat this condition, in particular when there is an increased risk of complications. Frontiers Media S.A. 2021-10-04 /pmc/articles/PMC8520941/ /pubmed/34671651 http://dx.doi.org/10.3389/fcvm.2021.714826 Text en Copyright © 2021 Mirijello, Santoliquido, Piscitelli, Borelli, Serviddio, Simeone, Grandone and De Cosmo. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Cardiovascular Medicine
Mirijello, Antonio
Santoliquido, Mariateresa
Piscitelli, Pamela
Borelli, Cristina
Serviddio, Gaetano
Simeone, Anna
Grandone, Elvira
De Cosmo, Salvatore
Pulmonary Artery Stump Thrombosis: To Treat or Not to Treat? The Question Is Still Open. Description of a Case and Review of the Literature
title Pulmonary Artery Stump Thrombosis: To Treat or Not to Treat? The Question Is Still Open. Description of a Case and Review of the Literature
title_full Pulmonary Artery Stump Thrombosis: To Treat or Not to Treat? The Question Is Still Open. Description of a Case and Review of the Literature
title_fullStr Pulmonary Artery Stump Thrombosis: To Treat or Not to Treat? The Question Is Still Open. Description of a Case and Review of the Literature
title_full_unstemmed Pulmonary Artery Stump Thrombosis: To Treat or Not to Treat? The Question Is Still Open. Description of a Case and Review of the Literature
title_short Pulmonary Artery Stump Thrombosis: To Treat or Not to Treat? The Question Is Still Open. Description of a Case and Review of the Literature
title_sort pulmonary artery stump thrombosis: to treat or not to treat? the question is still open. description of a case and review of the literature
topic Cardiovascular Medicine
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520941/
https://www.ncbi.nlm.nih.gov/pubmed/34671651
http://dx.doi.org/10.3389/fcvm.2021.714826
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