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Pulmonary Artery Stump Thrombosis: To Treat or Not to Treat? The Question Is Still Open. Description of a Case and Review of the Literature
Pulmonary artery stump thrombosis (PAST) represents a possible complication after lung surgery. We report the case of a 59-year-old man who presented with dyspnoea about 4 years after right pneumonectomy due to squamous cell lung cancer. A CT-scan showed the presence of pulmonary artery stump thromb...
Autores principales: | , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Frontiers Media S.A.
2021
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520941/ https://www.ncbi.nlm.nih.gov/pubmed/34671651 http://dx.doi.org/10.3389/fcvm.2021.714826 |
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author | Mirijello, Antonio Santoliquido, Mariateresa Piscitelli, Pamela Borelli, Cristina Serviddio, Gaetano Simeone, Anna Grandone, Elvira De Cosmo, Salvatore |
author_facet | Mirijello, Antonio Santoliquido, Mariateresa Piscitelli, Pamela Borelli, Cristina Serviddio, Gaetano Simeone, Anna Grandone, Elvira De Cosmo, Salvatore |
author_sort | Mirijello, Antonio |
collection | PubMed |
description | Pulmonary artery stump thrombosis (PAST) represents a possible complication after lung surgery. We report the case of a 59-year-old man who presented with dyspnoea about 4 years after right pneumonectomy due to squamous cell lung cancer. A CT-scan showed the presence of pulmonary artery stump thrombosis. Although there was no evidence of pulmonary embolism, given the clinical features and radiological shape of the thrombus, anticoagulation treatment with low-molecular-weight heparin was started with improvement of symptoms. The patient was discharged on anticoagulant treatment and a pulmonary CT-scan performed 4 months later showed an almost complete resolution of the PAST. Pathophysiological mechanisms of PAST are still unknown, although several hypotheses have been proposed. However, the decision to treat PAST with anticoagulants is still controversial. A review of literature will be provided in order to discuss risk factors, possible etiologies and to highlight clinical and radiological characteristics that could suggest to treat this condition, in particular when there is an increased risk of complications. |
format | Online Article Text |
id | pubmed-8520941 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Frontiers Media S.A. |
record_format | MEDLINE/PubMed |
spelling | pubmed-85209412021-10-19 Pulmonary Artery Stump Thrombosis: To Treat or Not to Treat? The Question Is Still Open. Description of a Case and Review of the Literature Mirijello, Antonio Santoliquido, Mariateresa Piscitelli, Pamela Borelli, Cristina Serviddio, Gaetano Simeone, Anna Grandone, Elvira De Cosmo, Salvatore Front Cardiovasc Med Cardiovascular Medicine Pulmonary artery stump thrombosis (PAST) represents a possible complication after lung surgery. We report the case of a 59-year-old man who presented with dyspnoea about 4 years after right pneumonectomy due to squamous cell lung cancer. A CT-scan showed the presence of pulmonary artery stump thrombosis. Although there was no evidence of pulmonary embolism, given the clinical features and radiological shape of the thrombus, anticoagulation treatment with low-molecular-weight heparin was started with improvement of symptoms. The patient was discharged on anticoagulant treatment and a pulmonary CT-scan performed 4 months later showed an almost complete resolution of the PAST. Pathophysiological mechanisms of PAST are still unknown, although several hypotheses have been proposed. However, the decision to treat PAST with anticoagulants is still controversial. A review of literature will be provided in order to discuss risk factors, possible etiologies and to highlight clinical and radiological characteristics that could suggest to treat this condition, in particular when there is an increased risk of complications. Frontiers Media S.A. 2021-10-04 /pmc/articles/PMC8520941/ /pubmed/34671651 http://dx.doi.org/10.3389/fcvm.2021.714826 Text en Copyright © 2021 Mirijello, Santoliquido, Piscitelli, Borelli, Serviddio, Simeone, Grandone and De Cosmo. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms. |
spellingShingle | Cardiovascular Medicine Mirijello, Antonio Santoliquido, Mariateresa Piscitelli, Pamela Borelli, Cristina Serviddio, Gaetano Simeone, Anna Grandone, Elvira De Cosmo, Salvatore Pulmonary Artery Stump Thrombosis: To Treat or Not to Treat? The Question Is Still Open. Description of a Case and Review of the Literature |
title | Pulmonary Artery Stump Thrombosis: To Treat or Not to Treat? The Question Is Still Open. Description of a Case and Review of the Literature |
title_full | Pulmonary Artery Stump Thrombosis: To Treat or Not to Treat? The Question Is Still Open. Description of a Case and Review of the Literature |
title_fullStr | Pulmonary Artery Stump Thrombosis: To Treat or Not to Treat? The Question Is Still Open. Description of a Case and Review of the Literature |
title_full_unstemmed | Pulmonary Artery Stump Thrombosis: To Treat or Not to Treat? The Question Is Still Open. Description of a Case and Review of the Literature |
title_short | Pulmonary Artery Stump Thrombosis: To Treat or Not to Treat? The Question Is Still Open. Description of a Case and Review of the Literature |
title_sort | pulmonary artery stump thrombosis: to treat or not to treat? the question is still open. description of a case and review of the literature |
topic | Cardiovascular Medicine |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8520941/ https://www.ncbi.nlm.nih.gov/pubmed/34671651 http://dx.doi.org/10.3389/fcvm.2021.714826 |
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