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The Impact of Normal Saline or Balanced Crystalloid on Plasma Chloride Concentration and Acute Kidney Injury in Patients With Predicted Severe Acute Pancreatitis: Protocol of a Phase II, Multicenter, Stepped-Wedge, Cluster-Randomized, Controlled Trial

Introduction/aim: The supraphysiologic chloride concentration of normal saline may contribute to acute kidney injury (AKI). Balanced crystalloids can decrease chloride concentration and AKI in critically ill patients. We aim to test the hypothesis that, in patients with predicted severe acute pancre...

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Detalles Bibliográficos
Autores principales: Ye, Bo, Huang, Mingfeng, Chen, Tao, Doig, Gordon, Wu, Bin, Chen, Mingzhi, Tu, Shumin, Chen, Xiaomei, Yang, Mei, Zhang, Guoxiu, Li, Qiang, Pan, Xinting, Zhao, Lijuan, Xia, Honghai, Chen, Yan, Ke, Lu, Tong, Zhihui, Bellomo, Rinaldo, Windsor, John, Li, Weiqin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521113/
https://www.ncbi.nlm.nih.gov/pubmed/34671619
http://dx.doi.org/10.3389/fmed.2021.731955

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