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Epidemiological review of leprosy in WHO’s Western Pacific Region: 1991–2019

BACKGROUND: Leprosy elimination was achieved in the Western Pacific Region of the World Health Organization (WHO) in the late 1980s. However, cases continue to be reported within the Region. This paper analyses leprosy cases in the Region reported to WHO during 1991–2019. METHODS: Descriptive analys...

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Autores principales: Rahevar, Kalpeshsinh, Morishita, Fukushi, Oh, Kyung Hyun, Islam, Tauhid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: World Health Organization 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521134/
https://www.ncbi.nlm.nih.gov/pubmed/34703634
http://dx.doi.org/10.5365/wpsar.2021.12.3.858
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author Rahevar, Kalpeshsinh
Morishita, Fukushi
Oh, Kyung Hyun
Islam, Tauhid
author_facet Rahevar, Kalpeshsinh
Morishita, Fukushi
Oh, Kyung Hyun
Islam, Tauhid
author_sort Rahevar, Kalpeshsinh
collection PubMed
description BACKGROUND: Leprosy elimination was achieved in the Western Pacific Region of the World Health Organization (WHO) in the late 1980s. However, cases continue to be reported within the Region. This paper analyses leprosy cases in the Region reported to WHO during 1991–2019. METHODS: Descriptive analyses were conducted of data from leprosy surveillance reported in the Region. Key indicators included prevalence, the number and rate of new cases detected, proportions of cases with multibacillary leprosy or grade 2 disability, and the numbers and proportions of cases among children and cases by sex. RESULTS: From 1991 to 2019, the number of registered cases detected in the Region decreased by 94% (from 68 313 in 1991 to 4381 in 2019), and the number of new cases detected decreased by 72.1% (from 15 002 in 1991 to 4004 in 2019). The proportion of cases of multibacillary leprosy increased from 67.4% (8045/11 943) in 1995 to 85.6% (3428/4004) in 2019, and between 1997 and 2019 the number of leprosy cases occurring in children decreased from 1240 to 424. The proportion of new cases with grade 2 disability decreased from 15.4% in 1997 to 6.6% in 2019. With few exceptions, nearly two thirds of reported cases occurred in males. CONCLUSION: Most countries and areas in the Region have successfully eliminated leprosy, although some pockets remain in countries with hard-to-reach areas. The introduction of multidrug therapy and WHO’s 1991 elimination goals may have prompted the initial decline in leprosy cases. Continued efforts are required in case-finding, care and prevention in areas with a high burden of disease.
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spelling pubmed-85211342021-10-25 Epidemiological review of leprosy in WHO’s Western Pacific Region: 1991–2019 Rahevar, Kalpeshsinh Morishita, Fukushi Oh, Kyung Hyun Islam, Tauhid Western Pac Surveill Response J Non Theme Issue BACKGROUND: Leprosy elimination was achieved in the Western Pacific Region of the World Health Organization (WHO) in the late 1980s. However, cases continue to be reported within the Region. This paper analyses leprosy cases in the Region reported to WHO during 1991–2019. METHODS: Descriptive analyses were conducted of data from leprosy surveillance reported in the Region. Key indicators included prevalence, the number and rate of new cases detected, proportions of cases with multibacillary leprosy or grade 2 disability, and the numbers and proportions of cases among children and cases by sex. RESULTS: From 1991 to 2019, the number of registered cases detected in the Region decreased by 94% (from 68 313 in 1991 to 4381 in 2019), and the number of new cases detected decreased by 72.1% (from 15 002 in 1991 to 4004 in 2019). The proportion of cases of multibacillary leprosy increased from 67.4% (8045/11 943) in 1995 to 85.6% (3428/4004) in 2019, and between 1997 and 2019 the number of leprosy cases occurring in children decreased from 1240 to 424. The proportion of new cases with grade 2 disability decreased from 15.4% in 1997 to 6.6% in 2019. With few exceptions, nearly two thirds of reported cases occurred in males. CONCLUSION: Most countries and areas in the Region have successfully eliminated leprosy, although some pockets remain in countries with hard-to-reach areas. The introduction of multidrug therapy and WHO’s 1991 elimination goals may have prompted the initial decline in leprosy cases. Continued efforts are required in case-finding, care and prevention in areas with a high burden of disease. World Health Organization 2021-08-23 /pmc/articles/PMC8521134/ /pubmed/34703634 http://dx.doi.org/10.5365/wpsar.2021.12.3.858 Text en (c) 2021 The authors; licensee World Health Organization. https://creativecommons.org/licenses/by/3.0/igo/This is an open access article distributed under the terms of the Creative Commons Attribution IGO License (http://creativecommons.org/licenses/by/3.0/igo/legalcode (https://creativecommons.org/licenses/by/3.0/igo/) ), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. In any reproduction of this article there should not be any suggestion that WHO or this article endorse any specific organization or products. The use of the WHO logo is not permitted. This notice should be preserved along with the article's original URL.
spellingShingle Non Theme Issue
Rahevar, Kalpeshsinh
Morishita, Fukushi
Oh, Kyung Hyun
Islam, Tauhid
Epidemiological review of leprosy in WHO’s Western Pacific Region: 1991–2019
title Epidemiological review of leprosy in WHO’s Western Pacific Region: 1991–2019
title_full Epidemiological review of leprosy in WHO’s Western Pacific Region: 1991–2019
title_fullStr Epidemiological review of leprosy in WHO’s Western Pacific Region: 1991–2019
title_full_unstemmed Epidemiological review of leprosy in WHO’s Western Pacific Region: 1991–2019
title_short Epidemiological review of leprosy in WHO’s Western Pacific Region: 1991–2019
title_sort epidemiological review of leprosy in who’s western pacific region: 1991–2019
topic Non Theme Issue
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521134/
https://www.ncbi.nlm.nih.gov/pubmed/34703634
http://dx.doi.org/10.5365/wpsar.2021.12.3.858
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