Cargando…

Computational Inference, Validation, and Analysis of 5’UTR-Leader Sequences of Alleles of Immunoglobulin Heavy Chain Variable Genes

Upstream and downstream sequences of immunoglobulin genes may affect the expression of such genes. However, these sequences are rarely studied or characterized in most studies of immunoglobulin repertoires. Inference from large, rearranged immunoglobulin transcriptome data sets offers an opportunity...

Descripción completa

Detalles Bibliográficos
Autores principales:	Huang, Yixun, Thörnqvist, Linnea, Ohlin, Mats
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Immunology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521166/ https://www.ncbi.nlm.nih.gov/pubmed/34671351 http://dx.doi.org/10.3389/fimmu.2021.730105

Ejemplares similares

Data on the nucleotide composition of the first codons encoding the complementary determining region 3 (CDR3) in immunoglobulin heavy chains
por: Thörnqvist, Linnea, et al.
Publicado: (2018)

Poorly Expressed Alleles of Several Human Immunoglobulin Heavy Chain Variable Genes are Common in the Human Population
por: Ohlin, Mats
Publicado: (2021)

Inferred Allelic Variants of Immunoglobulin Receptor Genes: A System for Their Evaluation, Documentation, and Naming
por: Ohlin, Mats, et al.
Publicado: (2019)

In Vitro Evolution of Antibodies Inspired by In Vivo Evolution
por: Persson, Helena, et al.
Publicado: (2018)

Antibody Heavy Chain Variable Domains of Different Germline Gene Origins Diversify through Different Paths
por: Kirik, Ufuk, et al.
Publicado: (2017)

Maturation of the Human Immunoglobulin Heavy Chain Repertoire With Age
por: Ghraichy, Marie, et al.
Publicado: (2020)

Data on haplotype-supported immunoglobulin germline gene inference
por: Kirik, Ufuk, et al.
Publicado: (2017)

Linear Epitope Binding Patterns of Grass Pollen-Specific Antibodies in Allergy and in Response to Allergen-Specific Immunotherapy
por: Thörnqvist, Linnea, et al.
Publicado: (2022)

Immunoglobulin light chain allelic inclusion in systemic lupus erythematosus
por: Fraser, Louise D., et al.
Publicado: (2015)

Epigenetic Regulation of Individual Modules of the immunoglobulin heavy chain locus 3′ Regulatory Region
por: Birshtein, Barbara K.
Publicado: (2014)

Characterization of DNA G-Quadruplex Structures in Human Immunoglobulin Heavy Variable (IGHV) Genes
por: Tang, Catherine, et al.
Publicado: (2021)

A Novel Framework for Characterizing Genomic Haplotype Diversity in the Human Immunoglobulin Heavy Chain Locus
por: Rodriguez, Oscar L., et al.
Publicado: (2020)

Serum Free Immunoglobulins Light Chains: A Common Feature of Common Variable Immunodeficiency?
por: Guevara-Hoyer, Kissy, et al.
Publicado: (2020)

Immunoglobulin Analysis Tool: A Novel Tool for the Analysis of Human and Mouse Heavy and Light Chain Transcripts
por: Rogosch, Tobias, et al.
Publicado: (2012)

Frequency Patterns of T-Cell Exposed Amino Acid Motifs in Immunoglobulin Heavy Chain Peptides Presented by MHCs
por: Bremel, Robert D., et al.
Publicado: (2014)

A deletion map of the human immunoglobulin heavy chain variable region
Publicado: (1991)

Organization of the variable region of the immunoglobulin heavy-chain gene locus of the rat
por: Hendricks, Jacobus, et al.
Publicado: (2010)

Polymorphisms in human immunoglobulin heavy chain variable genes and their upstream regions
por: Mikocziova, Ivana, et al.
Publicado: (2020)

Estimating Copy Number and Allelic Variation at the Immunoglobulin Heavy Chain Locus Using Short Reads
por: Luo, Shishi, et al.
Publicado: (2016)

The Complete Nucleotide Sequence of the Human Immunoglobulin Heavy Chain Variable Region Locus
por: Matsuda, Fumihiko, et al.
Publicado: (1998)

Evidence for gene conversion among immunoglobulin heavy chain variable region genes
Publicado: (1984)

DNA Sequence of Immunoglobulin Heavy Chain Variable Region Gene in Thyroid Lymphoma
por: Miwa, Hideaki, et al.
Publicado: (2001)

Allelic exclusion of the immunoglobulin heavy chain locus is independent of its nuclear localization in mature B cells
por: Holwerda, Sjoerd J. B., et al.
Publicado: (2013)

Association between a common immunoglobulin heavy chain allele and rheumatic heart disease risk in Oceania
por: Parks, Tom, et al.
Publicado: (2017)

Construction of a Large Size Human Immunoglobulin Heavy Chain Variable (VH) Domain Library, Isolation and Characterization of Novel Human Antibody VH Domains Targeting PD-L1 and CD22
por: Sun, Zehua, et al.
Publicado: (2022)

Immunoglobulin Heavy Chain Exclusion in the Shark
por: Malecek, Karolina, et al.
Publicado: (2008)

Unveiling the Diversity of Immunoglobulin Heavy Constant Gamma (IGHG) Gene Segments in Brazilian Populations Reveals 28 Novel Alleles and Evidence of Gene Conversion and Natural Selection
por: Calonga-Solís, Verónica, et al.
Publicado: (2019)

Acquisition of N-Glycosylation Sites in Immunoglobulin Heavy Chain Genes During Local Expansion in Parotid Salivary Glands of Primary Sjögren Patients
por: Visser, Annie, et al.
Publicado: (2018)

Identification of Subject-Specific Immunoglobulin Alleles From Expressed Repertoire Sequencing Data
por: Gadala-Maria, Daniel, et al.
Publicado: (2019)

Degenerate primer design to clone the human repertoire of immunoglobulin heavy chain variable regions
por: Sun, Ying, et al.
Publicado: (2011)

Extended Duration of DH–JH Rearrangement in Immunoglobulin Heavy Chain Transgenic Mice: Implications for Regulation of Allelic Exclusion
por: Chang, Yung, et al.
Publicado: (1999)

Killer Immunoglobulin-Like Receptor Allele Determination Using Next-Generation Sequencing Technology
por: Maniangou, Bercelin, et al.
Publicado: (2017)

V(H) Replacement Footprint Analyzer-I, a Java-Based Computer Program for Analyses of Immunoglobulin Heavy Chain Genes and Potential V(H) Replacement Products in Human and Mouse
por: Huang, Lin, et al.
Publicado: (2014)

Immunoglobulin heavy chains in medaka (Oryzias latipes)
por: Magadán-Mompó, Susana, et al.
Publicado: (2011)

Alterations of the gut microbiota in patients with immunoglobulin light chain amyloidosis
por: Yan, Jipeng, et al.
Publicado: (2022)

Commentary on Population matched (pm) germline allelic variants of immunoglobulin (IG) loci: relevance in infectious diseases and vaccination studies in human populations
por: Collins, Andrew M., et al.
Publicado: (2021)

Degenerated primer design to amplify the heavy chain variable region from immunoglobulin cDNA
por: Wang, Ying, et al.
Publicado: (2006)

Autoantibodies encoded by the most Jh-proximal human immunoglobulin heavy chain variable region gene
Publicado: (1989)

Receptor Revision of Immunoglobulin Heavy Chain Variable Region Genes in Normal Human B Lymphocytes
por: Wilson, Patrick C., et al.
Publicado: (2000)

Genotyping and Copy Number Analysis of Immunoglobulin Heavy Chain Variable Genes Using Long Reads
por: Ford, Michael, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_kgp7uqq816a33llg503mes1bek