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Stochastic model of the transmission dynamics of COVID-19 pandemic

In this paper, we formulate an SVITR deterministic model and extend it to a stochastic model by introducing intensity of stochastic factors and Brownian motion. Our basic qualitative analysis of both models includes the positivity of the solution, invariant region, disease-free equilibrium point, ba...

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Autores principales: Tesfaye, Aychew Wondyfraw, Satana, Tesfaye Sama
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521301/
https://www.ncbi.nlm.nih.gov/pubmed/34691161
http://dx.doi.org/10.1186/s13662-021-03597-1
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author Tesfaye, Aychew Wondyfraw
Satana, Tesfaye Sama
author_facet Tesfaye, Aychew Wondyfraw
Satana, Tesfaye Sama
author_sort Tesfaye, Aychew Wondyfraw
collection PubMed
description In this paper, we formulate an SVITR deterministic model and extend it to a stochastic model by introducing intensity of stochastic factors and Brownian motion. Our basic qualitative analysis of both models includes the positivity of the solution, invariant region, disease-free equilibrium point, basic reproduction number, local and global stability of disease-free equilibrium point, endemic equilibrium point, and sensitivity. We obtain the stochastic reproduction number and local stability by using twice differentiable Itô’s formula. We prove the global stability of the disease-free equilibrium point by using a Lyapunov function. We determine the sensitivity of the effect of each parameter on basic reproduction number of the model by using a normalized sensitivity index formula. On the other hand, we demonstrate numerical simulation results of deterministic and stochastic models of COVID-19 by using Maple 18 and MATLAB software. Our simulation results indicate that reducing the contact between infected and susceptible individuals and improvement of treatment play a vital role in COVID-19 pandemic control.
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spelling pubmed-85213012021-10-18 Stochastic model of the transmission dynamics of COVID-19 pandemic Tesfaye, Aychew Wondyfraw Satana, Tesfaye Sama Adv Differ Equ Research In this paper, we formulate an SVITR deterministic model and extend it to a stochastic model by introducing intensity of stochastic factors and Brownian motion. Our basic qualitative analysis of both models includes the positivity of the solution, invariant region, disease-free equilibrium point, basic reproduction number, local and global stability of disease-free equilibrium point, endemic equilibrium point, and sensitivity. We obtain the stochastic reproduction number and local stability by using twice differentiable Itô’s formula. We prove the global stability of the disease-free equilibrium point by using a Lyapunov function. We determine the sensitivity of the effect of each parameter on basic reproduction number of the model by using a normalized sensitivity index formula. On the other hand, we demonstrate numerical simulation results of deterministic and stochastic models of COVID-19 by using Maple 18 and MATLAB software. Our simulation results indicate that reducing the contact between infected and susceptible individuals and improvement of treatment play a vital role in COVID-19 pandemic control. Springer International Publishing 2021-10-18 2021 /pmc/articles/PMC8521301/ /pubmed/34691161 http://dx.doi.org/10.1186/s13662-021-03597-1 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Research
Tesfaye, Aychew Wondyfraw
Satana, Tesfaye Sama
Stochastic model of the transmission dynamics of COVID-19 pandemic
title Stochastic model of the transmission dynamics of COVID-19 pandemic
title_full Stochastic model of the transmission dynamics of COVID-19 pandemic
title_fullStr Stochastic model of the transmission dynamics of COVID-19 pandemic
title_full_unstemmed Stochastic model of the transmission dynamics of COVID-19 pandemic
title_short Stochastic model of the transmission dynamics of COVID-19 pandemic
title_sort stochastic model of the transmission dynamics of covid-19 pandemic
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521301/
https://www.ncbi.nlm.nih.gov/pubmed/34691161
http://dx.doi.org/10.1186/s13662-021-03597-1
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