RASSF1C oncogene elicits amoeboid invasion, cancer stemness, and extracellular vesicle release via a SRC/Rho axis

Cell plasticity is a crucial hallmark leading to cancer metastasis. Upregulation of Rho/ROCK pathway drives actomyosin contractility, protrusive forces, and contributes to the occurrence of highly invasive amoeboid cells in tumors. Cancer stem cells are similarly associated with metastasis, but how...

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Detalles Bibliográficos
Autores principales: Tognoli, Maria Laura, Vlahov, Nikola, Steenbeek, Sander, Grawenda, Anna M, Eyres, Michael, Cano‐Rodriguez, David, Scrace, Simon, Kartsonaki, Christiana, von Kriegsheim, Alex, Willms, Eduard, Wood, Matthew J, Rots, Marianne G, van Rheenen, Jacco, O'Neill, Eric, Pankova, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2021
Materias:
Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521318/
https://www.ncbi.nlm.nih.gov/pubmed/34532864
http://dx.doi.org/10.15252/embj.2021107680

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521318/
https://www.ncbi.nlm.nih.gov/pubmed/34532864
http://dx.doi.org/10.15252/embj.2021107680

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