Cargando…

Mice lacking melatonin MT2 receptors exhibit attentional deficits, anxiety and enhanced social interaction

BACKGROUND: Aside from regulating circadian rhythms, melatonin also affects cognitive processes, such as alertness, and modulates the brain circuitry underlying psychiatric diseases, such as depression, schizophrenia and bipolar disorder, via mechanisms that are not fully clear. In particular, while...

Descripción completa

Detalles Bibliográficos
Autores principales:	Thomson, David M, Mitchell, Emma J, Openshaw, Rebecca L, Pratt, Judith A, Morris, Brian J
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2021
Materias:	Original Papers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521347/ https://www.ncbi.nlm.nih.gov/pubmed/34304635 http://dx.doi.org/10.1177/02698811211032439

Ejemplares similares

16p11.2 deletion mice exhibit compromised fronto-temporal connectivity, GABAergic dysfunction, and enhanced attentional ability
por: Openshaw, Rebecca L., et al.
Publicado: (2023)

Mice haploinsufficient for Map2k7, a gene involved in neurodevelopment and risk for schizophrenia, show impaired attention, a vigilance decrement deficit and unstable cognitive processing in an attentional task: impact of minocycline
por: Openshaw, R.L., et al.
Publicado: (2016)

Drug-responsive autism phenotypes in the 16p11.2 deletion mouse model: a central role for gene-environment interactions
por: Mitchell, Emma J., et al.
Publicado: (2020)

The schizophrenia risk gene Map2k7 regulates responding in a novel contingency-shifting rodent touchscreen gambling task
por: Openshaw, Rebecca L., et al.
Publicado: (2022)

Melatonin MT(1) and MT(2) Receptors Exhibit Distinct Effects in the Modulation of Body Temperature across the Light/Dark Cycle
por: López-Canul, Martha, et al.
Publicado: (2019)

MT3 melatonin binding site, MT1 and MT2 melatonin receptors are present in oocyte, but only MT1 is present in bovine blastocyst produced in vitro
por: Sampaio, Rafael V, et al.
Publicado: (2012)

Melatonin MT(1) and MT(2) Receptors in the Ram Reproductive Tract
por: González-Arto, Marta, et al.
Publicado: (2017)

Pistacia vera Extract Potentiates the Effect of Melatonin on Human Melatonin MT(1) and MT(2) Receptors with Functional Selectivity
por: Labani, Nedjma, et al.
Publicado: (2023)

Map2k7 Haploinsufficiency Induces Brain Imaging Endophenotypes and Behavioral Phenotypes Relevant to Schizophrenia
por: Openshaw, Rebecca L, et al.
Publicado: (2020)

Human Gastroenteropancreatic Expression of Melatonin and Its Receptors MT1 and MT2
por: Söderquist, Fanny, et al.
Publicado: (2015)

New Radioligands for Describing the Molecular Pharmacology of MT(1) and MT(2) Melatonin Receptors
por: Legros, Céline, et al.
Publicado: (2013)

Differential Function of Melatonin MT(1) and MT(2) Receptors in REM and NREM Sleep
por: Gobbi, Gabriella, et al.
Publicado: (2019)

Inflammation, Anxiety, and Stress in Attention-Deficit/Hyperactivity Disorder
por: Saccaro, Luigi F., et al.
Publicado: (2021)

Cognitive deficits and anxiety induced by diisononyl phthalate in mice and the neuroprotective effects of melatonin
por: Ma, Ping, et al.
Publicado: (2015)

SUN-240 Female Mice Lacking Brain Insulin Production Exhibit Learning Deficits, Anxiety, and Reduced Hippocampal Cyclin D1 Expression
por: Baehring, Stella Katharina, et al.
Publicado: (2020)

Lack of correlation between hippocampal substructure atrophy and attention dysfunction in deficit schizophrenia
por: Li, Jin, et al.
Publicado: (2023)

Circadian Pattern of Melatonin MT1 and MT2 Receptor Localization in the Rat Suprachiasmatic Nucleus
por: Waly, Nermien E., et al.
Publicado: (2015)

Hamster Melatonin Receptors: Cloning and Binding Characterization of MT(1) and Attempt to Clone MT(2)
por: Gautier, Célia, et al.
Publicado: (2018)

Effects of melatonin in children with attention-deficit/hyperactivity disorder with sleep disorders after methylphenidate treatment
por: Masi, Gabriele, et al.
Publicado: (2019)

Evaluation of Anxiety Sensitivity, Anxiety, Depression, and Attention Deficit Hyperactivity Disorder in Patients with Tinnitus
por: Kumbul, Yusuf Çağdaş, et al.
Publicado: (2022)

Expression of the MT1 Melatonin Receptor in Ovarian Cancer Cells
por: Jablonska, Karolina, et al.
Publicado: (2014)

Mice Lacking the kf-1 Gene Exhibit Increased Anxiety- but not Despair-Like Behavior
por: Tsujimura, Atsushi, et al.
Publicado: (2008)

Adolescent sadfishing on social media: anxiety, depression, attention seeking, and lack of perceived social support as potential contributors
por: Shabahang, Reza, et al.
Publicado: (2023)

Endogenous and Exogenous Melatonin Exposure Attenuates Hepatic MT(1) Melatonin Receptor Protein Expression in Rat
por: Mathes, Alexander M., et al.
Publicado: (2019)

State, trait anxiety and selective attention differences in Attention Deficit Hyperactivity Disorder (ADHD) subtypes
por: González-Castro, Paloma, et al.
Publicado: (2015)

Lack of Neuropsychological Deficits in Generalized Social Phobia
por: Sutterby, Scott R., et al.
Publicado: (2012)

Structural basis for ligand recognition at the human MT(1) melatonin receptor
por: Stauch, Benjamin, et al.
Publicado: (2019)

Steroid sulfatase-deficient mice exhibit endophenotypes relevant to Attention Deficit Hyperactivity Disorder
por: Trent, Simon, et al.
Publicado: (2012)

Prognostic Impact of Melatonin Receptors MT1 and MT2 in Non-Small Cell Lung Cancer (NSCLC)
por: Jablonska, Karolina, et al.
Publicado: (2019)

Characterization of the various functional pathways elicited by synthetic agonists or antagonists at the melatonin MT(1) and MT(2) receptors
por: Legros, Céline, et al.
Publicado: (2019)

Structural Basis for Agonistic Activity and Selectivity toward Melatonin Receptors hMT1 and hMT2
por: Cantarini, Mattia, et al.
Publicado: (2023)

Mice lacking Ptprd exhibit deficits in goal-directed behavior and female-specific impairments in sensorimotor gating
por: Ho, Emily V., et al.
Publicado: (2023)

Working Memory in Attention Deficit/Hyperactivity Disorder is Characterized by a Lack of Specialization of Brain Function
por: Fassbender, Catherine, et al.
Publicado: (2011)

JNK signalling mediates aspects of maternal immune activation: importance of maternal genotype in relation to schizophrenia risk
por: Openshaw, Rebecca L., et al.
Publicado: (2019)

Lack of association between COMT gene and deficit/nondeficit schizophrenia
por: Wonodi, Ikwunga, et al.
Publicado: (2006)

Attention deficits without cortical neuronal deficits
por: Zénon, Alexandre, et al.
Publicado: (2012)

Continuity in features of anxiety and attention deficit/hyperactivity disorder in young preschool children
por: Overgaard, Kristin Romvig, et al.
Publicado: (2014)

Aetiological overlap between anxiety and attention deficit hyperactivity symptom dimensions in adolescence
por: Michelini, Giorgia, et al.
Publicado: (2014)

Anxiety and Somatic Symptoms in Children and Adolescents Diagnosed with Attention-Deficit Hyperactivity Disorder
por: Okyar, Esra, et al.
Publicado: (2023)

Connectivity supporting attention in children with attention deficit hyperactivity disorder
por: Barber, Anita D., et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_g53kitl4ltqucg0c1fsjot38pm