Chimeric Mouse With Humanized Liver Is an Appropriate Animal Model to Investigate Mode of Action for Porphyria-Mediated Hepatocytotoxicity

Porphyrinogenic compounds are known to induce porphyria-mediated hepatocellular injury and subsequent regenerative proliferation in rodents, ultimately leading to hepatocellular tumor induction. However, an appropriate in vivo experimental model to evaluate an effect of porphyrinogenic compounds on...

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Detalles Bibliográficos
Autores principales: Eguchi, Ayumi, Fukunaga, Satoki, Ogata, Keiko, Kushida, Masahiko, Asano, Hiroyuki, Cohen, Samuel M., Sukata, Tokuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2021
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521358/
https://www.ncbi.nlm.nih.gov/pubmed/34238059
http://dx.doi.org/10.1177/01926233211027474

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521358/
https://www.ncbi.nlm.nih.gov/pubmed/34238059
http://dx.doi.org/10.1177/01926233211027474

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