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Intrapulmonary pharmacokinetic profile of cefiderocol in mechanically ventilated patients with pneumonia

OBJECTIVES: Lung penetration of cefiderocol, a novel siderophore cephalosporin approved for treatment of nosocomial pneumonia, has previously been evaluated in healthy subjects. This study assessed the intrapulmonary pharmacokinetic profile of cefiderocol at steady state in hospitalized, mechanicall...

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Detalles Bibliográficos
Autores principales: Katsube, Takayuki, Nicolau, David P, Rodvold, Keith A, Wunderink, Richard G, Echols, Roger, Matsunaga, Yuko, Menon, Anju, Portsmouth, Simon, Wajima, Toshihiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521398/
https://www.ncbi.nlm.nih.gov/pubmed/34383901
http://dx.doi.org/10.1093/jac/dkab280