Cargando…

A case of coinfection of a pediatric patient with acute SARS-COV-2 with MIS-C and severe DENV-2 in Mexico: a case report

BACKGROUND: COVID-19 cases have been increasing since the epidemic started. One of the major concerns is how clinical symptomatology would behave after coinfection with another virus. CASE PRESENTATION: In this case report, a pediatric native patient from Estado de Mexico (EDOMEX), MEX had severe DE...

Descripción completa

Detalles Bibliográficos
Autores principales: Jose, Perez-Mendez Maria, Paola, Zarate-Segura, Eduardo, Davila-Gonzalez, Arturo, Servin-Monroy Monroy Osvaldo, Fernando, Bastida-Gonzalez
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521498/
https://www.ncbi.nlm.nih.gov/pubmed/34663252
http://dx.doi.org/10.1186/s12879-021-06765-6
_version_ 1784584912492298240
author Jose, Perez-Mendez Maria
Paola, Zarate-Segura
Eduardo, Davila-Gonzalez
Arturo, Servin-Monroy Monroy Osvaldo
Fernando, Bastida-Gonzalez
author_facet Jose, Perez-Mendez Maria
Paola, Zarate-Segura
Eduardo, Davila-Gonzalez
Arturo, Servin-Monroy Monroy Osvaldo
Fernando, Bastida-Gonzalez
author_sort Jose, Perez-Mendez Maria
collection PubMed
description BACKGROUND: COVID-19 cases have been increasing since the epidemic started. One of the major concerns is how clinical symptomatology would behave after coinfection with another virus. CASE PRESENTATION: In this case report, a pediatric native patient from Estado de Mexico (EDOMEX), MEX had severe DENV-2 and acute SARS-CoV-2 at the same time. The clinical features were severe thrombocytopenia, secondary septic shock, cerebral edema, pericardial effusion, fluid overload that exhibited bipalpebral edema in all four extremities, hemophagocytic lymphohistiocytosis (HLH), coronary artery ectasia (CAE), multisystemic inflammatory syndrome in children (MIS-C), and probable COVID-19 pneumonia or acute respiratory distress syndrome (ARDS) that triggered patient intubation. The patient presented unusual symptomatology according to the literature. After 15 days of intubation and 15 more days under surveillance, he was released without respiratory sequelae and without treatment after major clinical improvement. CONCLUSION: The aim of this manuscript is to present clinical challenges that coinfection may cause in pediatric patients, even though COVID-19 in children does not tend to be as severe as in other sectors of the population.
format Online
Article
Text
id pubmed-8521498
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-85214982021-10-18 A case of coinfection of a pediatric patient with acute SARS-COV-2 with MIS-C and severe DENV-2 in Mexico: a case report Jose, Perez-Mendez Maria Paola, Zarate-Segura Eduardo, Davila-Gonzalez Arturo, Servin-Monroy Monroy Osvaldo Fernando, Bastida-Gonzalez BMC Infect Dis Case Report BACKGROUND: COVID-19 cases have been increasing since the epidemic started. One of the major concerns is how clinical symptomatology would behave after coinfection with another virus. CASE PRESENTATION: In this case report, a pediatric native patient from Estado de Mexico (EDOMEX), MEX had severe DENV-2 and acute SARS-CoV-2 at the same time. The clinical features were severe thrombocytopenia, secondary septic shock, cerebral edema, pericardial effusion, fluid overload that exhibited bipalpebral edema in all four extremities, hemophagocytic lymphohistiocytosis (HLH), coronary artery ectasia (CAE), multisystemic inflammatory syndrome in children (MIS-C), and probable COVID-19 pneumonia or acute respiratory distress syndrome (ARDS) that triggered patient intubation. The patient presented unusual symptomatology according to the literature. After 15 days of intubation and 15 more days under surveillance, he was released without respiratory sequelae and without treatment after major clinical improvement. CONCLUSION: The aim of this manuscript is to present clinical challenges that coinfection may cause in pediatric patients, even though COVID-19 in children does not tend to be as severe as in other sectors of the population. BioMed Central 2021-10-18 /pmc/articles/PMC8521498/ /pubmed/34663252 http://dx.doi.org/10.1186/s12879-021-06765-6 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Case Report
Jose, Perez-Mendez Maria
Paola, Zarate-Segura
Eduardo, Davila-Gonzalez
Arturo, Servin-Monroy Monroy Osvaldo
Fernando, Bastida-Gonzalez
A case of coinfection of a pediatric patient with acute SARS-COV-2 with MIS-C and severe DENV-2 in Mexico: a case report
title A case of coinfection of a pediatric patient with acute SARS-COV-2 with MIS-C and severe DENV-2 in Mexico: a case report
title_full A case of coinfection of a pediatric patient with acute SARS-COV-2 with MIS-C and severe DENV-2 in Mexico: a case report
title_fullStr A case of coinfection of a pediatric patient with acute SARS-COV-2 with MIS-C and severe DENV-2 in Mexico: a case report
title_full_unstemmed A case of coinfection of a pediatric patient with acute SARS-COV-2 with MIS-C and severe DENV-2 in Mexico: a case report
title_short A case of coinfection of a pediatric patient with acute SARS-COV-2 with MIS-C and severe DENV-2 in Mexico: a case report
title_sort case of coinfection of a pediatric patient with acute sars-cov-2 with mis-c and severe denv-2 in mexico: a case report
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521498/
https://www.ncbi.nlm.nih.gov/pubmed/34663252
http://dx.doi.org/10.1186/s12879-021-06765-6
work_keys_str_mv AT joseperezmendezmaria acaseofcoinfectionofapediatricpatientwithacutesarscov2withmiscandseveredenv2inmexicoacasereport
AT paolazaratesegura acaseofcoinfectionofapediatricpatientwithacutesarscov2withmiscandseveredenv2inmexicoacasereport
AT eduardodavilagonzalez acaseofcoinfectionofapediatricpatientwithacutesarscov2withmiscandseveredenv2inmexicoacasereport
AT arturoservinmonroymonroyosvaldo acaseofcoinfectionofapediatricpatientwithacutesarscov2withmiscandseveredenv2inmexicoacasereport
AT fernandobastidagonzalez acaseofcoinfectionofapediatricpatientwithacutesarscov2withmiscandseveredenv2inmexicoacasereport
AT joseperezmendezmaria caseofcoinfectionofapediatricpatientwithacutesarscov2withmiscandseveredenv2inmexicoacasereport
AT paolazaratesegura caseofcoinfectionofapediatricpatientwithacutesarscov2withmiscandseveredenv2inmexicoacasereport
AT eduardodavilagonzalez caseofcoinfectionofapediatricpatientwithacutesarscov2withmiscandseveredenv2inmexicoacasereport
AT arturoservinmonroymonroyosvaldo caseofcoinfectionofapediatricpatientwithacutesarscov2withmiscandseveredenv2inmexicoacasereport
AT fernandobastidagonzalez caseofcoinfectionofapediatricpatientwithacutesarscov2withmiscandseveredenv2inmexicoacasereport