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Oral Pemphigus Vulgaris
Pemphigus is a chronic mucocutaneous autoimmune disease with the clinical feature of blisters that initially appear in the oral cavity and later in the skin. The dental professionals play an important role in diagnosing the disease. Early diagnosis and treatment determine the course and prognosis of...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cureus
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521543/ https://www.ncbi.nlm.nih.gov/pubmed/34671517 http://dx.doi.org/10.7759/cureus.18005 |
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author | Subadra, K S, Sathasivasubramanian Warrier S, Aravind |
author_facet | Subadra, K S, Sathasivasubramanian Warrier S, Aravind |
author_sort | Subadra, K |
collection | PubMed |
description | Pemphigus is a chronic mucocutaneous autoimmune disease with the clinical feature of blisters that initially appear in the oral cavity and later in the skin. The dental professionals play an important role in diagnosing the disease. Early diagnosis and treatment determine the course and prognosis of the disease. Systemic corticosteroids continue to be the standard therapy for pemphigus vulgaris (PV). Management of PV involves prolonged use of steroids to control the disease and prevent relapses, but associated adverse events constantly remain a great challenge. Regular periodic clinical evaluation of patients with pemphigus on steroids is mandatory. This article describes a case of a 50-year-old woman with multiple chronic ulcers in the oral cavity in whom the diagnosis of PV was made and treated. The case study is followed by a review of the literature including etiology, pathogenesis, clinical features, as well as the various diagnostic criteria and the therapeutic options of PV. |
format | Online Article Text |
id | pubmed-8521543 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Cureus |
record_format | MEDLINE/PubMed |
spelling | pubmed-85215432021-10-19 Oral Pemphigus Vulgaris Subadra, K S, Sathasivasubramanian Warrier S, Aravind Cureus Pathology Pemphigus is a chronic mucocutaneous autoimmune disease with the clinical feature of blisters that initially appear in the oral cavity and later in the skin. The dental professionals play an important role in diagnosing the disease. Early diagnosis and treatment determine the course and prognosis of the disease. Systemic corticosteroids continue to be the standard therapy for pemphigus vulgaris (PV). Management of PV involves prolonged use of steroids to control the disease and prevent relapses, but associated adverse events constantly remain a great challenge. Regular periodic clinical evaluation of patients with pemphigus on steroids is mandatory. This article describes a case of a 50-year-old woman with multiple chronic ulcers in the oral cavity in whom the diagnosis of PV was made and treated. The case study is followed by a review of the literature including etiology, pathogenesis, clinical features, as well as the various diagnostic criteria and the therapeutic options of PV. Cureus 2021-09-15 /pmc/articles/PMC8521543/ /pubmed/34671517 http://dx.doi.org/10.7759/cureus.18005 Text en Copyright © 2021, Subadra et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Pathology Subadra, K S, Sathasivasubramanian Warrier S, Aravind Oral Pemphigus Vulgaris |
title | Oral Pemphigus Vulgaris |
title_full | Oral Pemphigus Vulgaris |
title_fullStr | Oral Pemphigus Vulgaris |
title_full_unstemmed | Oral Pemphigus Vulgaris |
title_short | Oral Pemphigus Vulgaris |
title_sort | oral pemphigus vulgaris |
topic | Pathology |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521543/ https://www.ncbi.nlm.nih.gov/pubmed/34671517 http://dx.doi.org/10.7759/cureus.18005 |
work_keys_str_mv | AT subadrak oralpemphigusvulgaris AT ssathasivasubramanian oralpemphigusvulgaris AT warriersaravind oralpemphigusvulgaris |