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Oral Pemphigus Vulgaris

Pemphigus is a chronic mucocutaneous autoimmune disease with the clinical feature of blisters that initially appear in the oral cavity and later in the skin. The dental professionals play an important role in diagnosing the disease. Early diagnosis and treatment determine the course and prognosis of...

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Detalles Bibliográficos
Autores principales: Subadra, K, S, Sathasivasubramanian, Warrier S, Aravind
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cureus 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521543/
https://www.ncbi.nlm.nih.gov/pubmed/34671517
http://dx.doi.org/10.7759/cureus.18005
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author Subadra, K
S, Sathasivasubramanian
Warrier S, Aravind
author_facet Subadra, K
S, Sathasivasubramanian
Warrier S, Aravind
author_sort Subadra, K
collection PubMed
description Pemphigus is a chronic mucocutaneous autoimmune disease with the clinical feature of blisters that initially appear in the oral cavity and later in the skin. The dental professionals play an important role in diagnosing the disease. Early diagnosis and treatment determine the course and prognosis of the disease. Systemic corticosteroids continue to be the standard therapy for pemphigus vulgaris (PV). Management of PV involves prolonged use of steroids to control the disease and prevent relapses, but associated adverse events constantly remain a great challenge. Regular periodic clinical evaluation of patients with pemphigus on steroids is mandatory. This article describes a case of a 50-year-old woman with multiple chronic ulcers in the oral cavity in whom the diagnosis of PV was made and treated. The case study is followed by a review of the literature including etiology, pathogenesis, clinical features, as well as the various diagnostic criteria and the therapeutic options of PV.
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spelling pubmed-85215432021-10-19 Oral Pemphigus Vulgaris Subadra, K S, Sathasivasubramanian Warrier S, Aravind Cureus Pathology Pemphigus is a chronic mucocutaneous autoimmune disease with the clinical feature of blisters that initially appear in the oral cavity and later in the skin. The dental professionals play an important role in diagnosing the disease. Early diagnosis and treatment determine the course and prognosis of the disease. Systemic corticosteroids continue to be the standard therapy for pemphigus vulgaris (PV). Management of PV involves prolonged use of steroids to control the disease and prevent relapses, but associated adverse events constantly remain a great challenge. Regular periodic clinical evaluation of patients with pemphigus on steroids is mandatory. This article describes a case of a 50-year-old woman with multiple chronic ulcers in the oral cavity in whom the diagnosis of PV was made and treated. The case study is followed by a review of the literature including etiology, pathogenesis, clinical features, as well as the various diagnostic criteria and the therapeutic options of PV. Cureus 2021-09-15 /pmc/articles/PMC8521543/ /pubmed/34671517 http://dx.doi.org/10.7759/cureus.18005 Text en Copyright © 2021, Subadra et al. https://creativecommons.org/licenses/by/3.0/This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited.
spellingShingle Pathology
Subadra, K
S, Sathasivasubramanian
Warrier S, Aravind
Oral Pemphigus Vulgaris
title Oral Pemphigus Vulgaris
title_full Oral Pemphigus Vulgaris
title_fullStr Oral Pemphigus Vulgaris
title_full_unstemmed Oral Pemphigus Vulgaris
title_short Oral Pemphigus Vulgaris
title_sort oral pemphigus vulgaris
topic Pathology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521543/
https://www.ncbi.nlm.nih.gov/pubmed/34671517
http://dx.doi.org/10.7759/cureus.18005
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