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MiR-144-3p inhibits gastric cancer progression and stemness via directly targeting GLI2 involved in hedgehog pathway

BACKGROUND: Gastric cancer (GC) is the fifth most commonly diagnosed cancer worldwide. Due to the dismal prognosis, identifying novel therapeutic targets in GC is urgently needed. Evidences have shown that miRNAs played critical roles in the regulation of tumor initiation and progression. GLI family...

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Detalles Bibliográficos
Autores principales: Lu, Yixun, Zhang, Benlong, Wang, Baohua, Wu, Di, Wang, Chuang, Gao, Yunhe, Liang, Wenquan, Xi, Hongqing, Wang, Xinxin, Chen, Lin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8521984/
https://www.ncbi.nlm.nih.gov/pubmed/34657624
http://dx.doi.org/10.1186/s12967-021-03093-w

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