Cargando…

LIPUS inhibits inflammation and catabolism through the NF‐κB pathway in human degenerative nucleus pulposus cells

BACKGROUND: Low-intensity pulsed ultrasound (LIPUS) is a safe and noninvasive rehabilitative physical therapy with anti-inflammatory effects. The current study investigated the effect of LIPUS on the inflammation of nucleus pulposus (NP) cells and its underlying mechanism. METHODS: Human NP cells we...

Descripción completa

Detalles Bibliográficos
Autores principales:	Yi, Weiwei, Chen, Qing, Liu, Chuan, Li, Kaiting, Tao, Bailong, Tian, Guihua, Zhou, Lu, Li, Xiaohong, Shen, Jieliang, Liu, Bo, Hu, Zhenming, Wang, Dawu, Bai, Dingqun
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522043/ https://www.ncbi.nlm.nih.gov/pubmed/34663388 http://dx.doi.org/10.1186/s13018-021-02739-1

Ejemplares similares

SDF-1/CXCR4 axis induces apoptosis of human degenerative nucleus pulposus cells via the NF-κB pathway
por: LIU, ZONGCHAO, et al.
Publicado: (2016)

SIRT1 protects against apoptosis by promoting autophagy in degenerative human disc nucleus pulposus cells
por: Jiang, Wei, et al.
Publicado: (2014)

IL-1β induces apoptosis and autophagy via mitochondria pathway in human degenerative nucleus pulposus cells
por: Shen, Jieliang, et al.
Publicado: (2017)

Impact of NF-κB pathway on the apoptosis-inflammation-autophagy crosstalk in human degenerative nucleus pulposus cells
por: Yi, Weiwei, et al.
Publicado: (2019)

HO-1 induced autophagy protects against IL-1 β-mediated apoptosis in human nucleus pulposus cells by inhibiting NF-κB
por: Zou, Luetao, et al.
Publicado: (2020)

Protective effects of autophagy and NFE2L2 on reactive oxygen species-induced pyroptosis of human nucleus pulposus cells
por: Bai, Zhibiao, et al.
Publicado: (2020)

LDHA-Mediated Glycolytic Metabolism in Nucleus Pulposus Cells Is a Potential Therapeutic Target for Intervertebral Disc Degeneration
por: Wu, Longxi, et al.
Publicado: (2021)

Autophagy attenuates the catabolic effect during inflammatory conditions in nucleus pulposus cells, as sustained by NF-κB and JNK inhibition
por: XU, KANG, et al.
Publicado: (2015)

Collagen type II is downregulated in the degenerative nucleus pulposus and contributes to the degeneration and apoptosis of human nucleus pulposus cells
por: Lian, Chengjie, et al.
Publicado: (2017)

Taurine attenuates ER stress-associated apoptosis and catabolism in nucleus pulposus cells
por: Yang, Liuxie, et al.
Publicado: (2022)

Biologic Response of Degenerative Living Human Nucleus Pulposus Cells to Treatment with Cytokines
por: Kim, Sang Hyun, et al.
Publicado: (2015)

Autologous fibroblasts induce fibrosis of the nucleus pulposus to maintain the stability of degenerative intervertebral discs
por: Chen, Chen, et al.
Publicado: (2020)

Urolithin A Inhibits the Catabolic Effect of TNFα on Nucleus Pulposus Cell and Alleviates Intervertebral Disc Degeneration in vivo
por: Liu, Huiyong, et al.
Publicado: (2018)

Knockdown Epithelial Membrane Protein 1 Suppresses Human Degenerative Intervertebral Disc–Derived Nucleus Pulposus Cell Proliferation
por: Li, Zhi-Yong, et al.
Publicado: (2011)

MicroRNA-494 promotes apoptosis and extracellular matrix degradation in degenerative human nucleus pulposus cells
por: Kang, Liang, et al.
Publicado: (2017)

Osteogenic protein-1 alleviates high glucose microenvironment-caused degenerative changes in nucleus pulposus cells
por: Liu, Ziming, et al.
Publicado: (2019)

Ghrelin protects against nucleus pulposus degeneration through inhibition of NF-κB signaling pathway and activation of Akt signaling pathway
por: Li, Weiwei, et al.
Publicado: (2017)

NF‐κB signalling pathways in nucleus pulposus cell function and intervertebral disc degeneration
por: Zhang, Guang‐Zhi, et al.
Publicado: (2021)

Injectable Hydrogel Combined with Nucleus Pulposus-Derived Mesenchymal Stem Cells for the Treatment of Degenerative Intervertebral Disc in Rats
por: Wang, Feng, et al.
Publicado: (2019)

HSP90 Inhibitor 17-AAG Attenuates Nucleus Pulposus Inflammation and Catabolism Induced by M1-Polarized Macrophages
por: Zhang, Shuo, et al.
Publicado: (2022)

Degenerate intervertebral disc‐like pH induces a catabolic mechanoresponse in human nucleus pulposus cells
por: Hodson, Nathan W., et al.
Publicado: (2018)

Effects of the NF-κB/p53 signaling pathway on intervertebral disc nucleus pulposus degeneration
por: Zhang, Litao, et al.
Publicado: (2020)

Chromobox homolog 4 overexpression inhibits TNF-α-induced matrix catabolism and senescence by suppressing activation of NF-κB signaling pathway in nucleus pulposus cells: CBX4 overexpression inhibits TNF-α-induced matrix catabolism and senescence
por: Zhang, Yangyang, et al.
Publicado: (2022)

Mitochondrial DNA induces nucleus pulposus cell pyroptosis via the TLR9-NF-κB-NLRP3 axis
por: Lu, Peng, et al.
Publicado: (2023)

Advanced glycation end products regulate anabolic and catabolic activities via NLRP3‐inflammasome activation in human nucleus pulposus cells
por: Song, Yu, et al.
Publicado: (2017)

Single-Cell RNA Sequencing Reveals the Difference in Human Normal and Degenerative Nucleus Pulposus Tissue Profiles and Cellular Interactions
por: Li, Zhencong, et al.
Publicado: (2022)

Luteoloside Inhibits IL-1β-Induced Apoptosis and Catabolism in Nucleus Pulposus Cells and Ameliorates Intervertebral Disk Degeneration
por: Lin, Jialiang, et al.
Publicado: (2019)

Circular RNA GRB10 as a competitive endogenous RNA regulating nucleus pulposus cells death in degenerative intervertebral disk
por: Guo, Wei, et al.
Publicado: (2018)

Comment to a BMJ Editorial Is LIPUS the baby in the bathwater?
por: Aspenberg, Per
Publicado: (2017)

USP15 promotes the apoptosis of degenerative nucleus pulposus cells by suppressing the PI3K/AKT signalling pathway
por: Yu, Bin, et al.
Publicado: (2020)

LIPUS as a potential strategy for periodontitis treatment: A review of the mechanisms
por: Aimaijiang, Maierhaba, et al.
Publicado: (2023)

Degenerative Nucleus Pulposus Cells Derived Exosomes Promoted Cartilage Endplate Cells Apoptosis and Aggravated Intervertebral Disc Degeneration
por: Feng, Xiaofei, et al.
Publicado: (2022)

Corrigendum: Single-cell RNA sequencing reveals the difference in human normal and degenerative nucleus pulposus tissue profiles and cellular interactions
por: Li, Zhencong, et al.
Publicado: (2023)

Corrigendum: Single-cell RNA sequencing reveals the difference in human normal and degenerative nucleus pulposus tissue profiles and cellular interactions
por: Li, Zhencong, et al.
Publicado: (2022)

Co-culturing nucleus pulposus mesenchymal stem cells with notochordal cell-rich nucleus pulposus explants attenuates tumor necrosis factor-α-induced senescence
por: Li, Xiao-Chuan, et al.
Publicado: (2018)

An analysis of the transcriptional landscape in hypoxia-treated primary nucleus pulposus cells
por: Peng, Zhicai, et al.
Publicado: (2023)

Inducing Angiogenesis in the Nucleus Pulposus
por: Damle, Sheela R., et al.
Publicado: (2023)

Rosuvastatin suppresses TNF-α-induced matrix catabolism, pyroptosis and senescence via the HMGB1/NF-κB signaling pathway in nucleus pulposus cells: Role of rosuvastatin in alleviating intervertebral disc degeneration
por: Chen, Weijian, et al.
Publicado: (2023)

Molecular Therapy for Degenerative Disc Disease: Clues from Secretome Analysis of the Notochordal Cell-Rich Nucleus Pulposus
por: Matta, Ajay, et al.
Publicado: (2017)

Potential of Human Nucleus Pulposus-Like Cells Derived From Umbilical Cord to Treat Degenerative Disc Disease
por: Perez-Cruet, Mick, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_5jh3i1ctgkgikpmpldakei7l1b