Cargando…

The global prevalence of osteoporosis in the world: a comprehensive systematic review and meta-analysis

BACKGROUND: Osteoporosis affects all sections of society, including families with people affected by osteoporosis, government agencies and medical institutes in various fields. For example, it involves the patient and his/her family members, and government agencies in terms of the cost of treatment...

Descripción completa

Detalles Bibliográficos
Autores principales: Salari, Nader, Ghasemi, Hooman, Mohammadi, Loghman, Behzadi, Mohammad hasan, Rabieenia, Elham, Shohaimi, Shamarina, Mohammadi, Masoud
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522202/
https://www.ncbi.nlm.nih.gov/pubmed/34657598
http://dx.doi.org/10.1186/s13018-021-02772-0
_version_ 1784585046942810112
author Salari, Nader
Ghasemi, Hooman
Mohammadi, Loghman
Behzadi, Mohammad hasan
Rabieenia, Elham
Shohaimi, Shamarina
Mohammadi, Masoud
author_facet Salari, Nader
Ghasemi, Hooman
Mohammadi, Loghman
Behzadi, Mohammad hasan
Rabieenia, Elham
Shohaimi, Shamarina
Mohammadi, Masoud
author_sort Salari, Nader
collection PubMed
description BACKGROUND: Osteoporosis affects all sections of society, including families with people affected by osteoporosis, government agencies and medical institutes in various fields. For example, it involves the patient and his/her family members, and government agencies in terms of the cost of treatment and medical care. Providing a comprehensive picture of the prevalence of osteoporosis globally is important for health policymakers to make appropriate decisions. Therefore, this study was conducted to investigate the prevalence of osteoporosis worldwide. METHODS: A systematic review and meta-analysis were conducted in accordance with the PRISMA criteria. The PubMed, Science Direct, Web of Science, Scopus, Magiran, and Google Scholar databases were searched with no lower time limit up till 26 August 2020. The heterogeneity of the studies was measured using the I(2) test, and the publication bias was assessed by the Begg and Mazumdar’s test at the significance level of 0.1. RESULTS: After following the systematic review processes, 86 studies were selected for meta-analysis. The sample size of the study was 103,334,579 people in the age range of 15–105 years. Using meta-analysis, the prevalence of osteoporosis in the world was reported to be 18.3 (95% CI 16.2–20.7). Based on 70 studies and sample size of 800,457 women, and heterogenicity I(2): 99.8, the prevalence of osteoporosis in women of the world was reported to be 23.1 (95% CI 19.8–26.9), while the prevalence of osteoporosis among men of the world was found to be 11.7 (95% CI 9.6–14.1 which was based on 40 studies and sample size of 453,964 men.). The highest prevalence of osteoporosis was reported in Africa with 39.5% (95% CI 22.3–59.7) and a sample size of 2989 people with the age range 18–95 years. CONCLUSION: According to the medical, economic, and social burden of osteoporosis, providing a robust and comprehensive estimate of the prevalence of osteoporosis in the world can facilitate decisions in health system planning and policymaking, including an overview of the current and outlook for the future; provide the necessary facilities for the treatment of people with osteoporosis; reduce the severe risks that lead to death by preventing fractures; and, finally, monitor the overall state of osteoporosis in the world. This study is the first to report a structured review and meta-analysis of the prevalence of osteoporosis worldwide.
format Online
Article
Text
id pubmed-8522202
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher BioMed Central
record_format MEDLINE/PubMed
spelling pubmed-85222022021-10-21 The global prevalence of osteoporosis in the world: a comprehensive systematic review and meta-analysis Salari, Nader Ghasemi, Hooman Mohammadi, Loghman Behzadi, Mohammad hasan Rabieenia, Elham Shohaimi, Shamarina Mohammadi, Masoud J Orthop Surg Res Systematic Review BACKGROUND: Osteoporosis affects all sections of society, including families with people affected by osteoporosis, government agencies and medical institutes in various fields. For example, it involves the patient and his/her family members, and government agencies in terms of the cost of treatment and medical care. Providing a comprehensive picture of the prevalence of osteoporosis globally is important for health policymakers to make appropriate decisions. Therefore, this study was conducted to investigate the prevalence of osteoporosis worldwide. METHODS: A systematic review and meta-analysis were conducted in accordance with the PRISMA criteria. The PubMed, Science Direct, Web of Science, Scopus, Magiran, and Google Scholar databases were searched with no lower time limit up till 26 August 2020. The heterogeneity of the studies was measured using the I(2) test, and the publication bias was assessed by the Begg and Mazumdar’s test at the significance level of 0.1. RESULTS: After following the systematic review processes, 86 studies were selected for meta-analysis. The sample size of the study was 103,334,579 people in the age range of 15–105 years. Using meta-analysis, the prevalence of osteoporosis in the world was reported to be 18.3 (95% CI 16.2–20.7). Based on 70 studies and sample size of 800,457 women, and heterogenicity I(2): 99.8, the prevalence of osteoporosis in women of the world was reported to be 23.1 (95% CI 19.8–26.9), while the prevalence of osteoporosis among men of the world was found to be 11.7 (95% CI 9.6–14.1 which was based on 40 studies and sample size of 453,964 men.). The highest prevalence of osteoporosis was reported in Africa with 39.5% (95% CI 22.3–59.7) and a sample size of 2989 people with the age range 18–95 years. CONCLUSION: According to the medical, economic, and social burden of osteoporosis, providing a robust and comprehensive estimate of the prevalence of osteoporosis in the world can facilitate decisions in health system planning and policymaking, including an overview of the current and outlook for the future; provide the necessary facilities for the treatment of people with osteoporosis; reduce the severe risks that lead to death by preventing fractures; and, finally, monitor the overall state of osteoporosis in the world. This study is the first to report a structured review and meta-analysis of the prevalence of osteoporosis worldwide. BioMed Central 2021-10-17 /pmc/articles/PMC8522202/ /pubmed/34657598 http://dx.doi.org/10.1186/s13018-021-02772-0 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/ (https://creativecommons.org/publicdomain/zero/1.0/) ) applies to the data made available in this article, unless otherwise stated in a credit line to the data.
spellingShingle Systematic Review
Salari, Nader
Ghasemi, Hooman
Mohammadi, Loghman
Behzadi, Mohammad hasan
Rabieenia, Elham
Shohaimi, Shamarina
Mohammadi, Masoud
The global prevalence of osteoporosis in the world: a comprehensive systematic review and meta-analysis
title The global prevalence of osteoporosis in the world: a comprehensive systematic review and meta-analysis
title_full The global prevalence of osteoporosis in the world: a comprehensive systematic review and meta-analysis
title_fullStr The global prevalence of osteoporosis in the world: a comprehensive systematic review and meta-analysis
title_full_unstemmed The global prevalence of osteoporosis in the world: a comprehensive systematic review and meta-analysis
title_short The global prevalence of osteoporosis in the world: a comprehensive systematic review and meta-analysis
title_sort global prevalence of osteoporosis in the world: a comprehensive systematic review and meta-analysis
topic Systematic Review
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522202/
https://www.ncbi.nlm.nih.gov/pubmed/34657598
http://dx.doi.org/10.1186/s13018-021-02772-0
work_keys_str_mv AT salarinader theglobalprevalenceofosteoporosisintheworldacomprehensivesystematicreviewandmetaanalysis
AT ghasemihooman theglobalprevalenceofosteoporosisintheworldacomprehensivesystematicreviewandmetaanalysis
AT mohammadiloghman theglobalprevalenceofosteoporosisintheworldacomprehensivesystematicreviewandmetaanalysis
AT behzadimohammadhasan theglobalprevalenceofosteoporosisintheworldacomprehensivesystematicreviewandmetaanalysis
AT rabieeniaelham theglobalprevalenceofosteoporosisintheworldacomprehensivesystematicreviewandmetaanalysis
AT shohaimishamarina theglobalprevalenceofosteoporosisintheworldacomprehensivesystematicreviewandmetaanalysis
AT mohammadimasoud theglobalprevalenceofosteoporosisintheworldacomprehensivesystematicreviewandmetaanalysis
AT salarinader globalprevalenceofosteoporosisintheworldacomprehensivesystematicreviewandmetaanalysis
AT ghasemihooman globalprevalenceofosteoporosisintheworldacomprehensivesystematicreviewandmetaanalysis
AT mohammadiloghman globalprevalenceofosteoporosisintheworldacomprehensivesystematicreviewandmetaanalysis
AT behzadimohammadhasan globalprevalenceofosteoporosisintheworldacomprehensivesystematicreviewandmetaanalysis
AT rabieeniaelham globalprevalenceofosteoporosisintheworldacomprehensivesystematicreviewandmetaanalysis
AT shohaimishamarina globalprevalenceofosteoporosisintheworldacomprehensivesystematicreviewandmetaanalysis
AT mohammadimasoud globalprevalenceofosteoporosisintheworldacomprehensivesystematicreviewandmetaanalysis