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PACmn for improved optogenetic control of intracellular cAMP

BACKGROUND: Cyclic adenosine monophosphate (cAMP) is a ubiquitous second messenger that transduces extracellular signals in virtually all eukaryotic cells. The soluble Beggiatoa photoactivatable adenylyl cyclase (bPAC) rapidly raises cAMP in blue light and has been used to study cAMP signaling pathw...

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Detalles Bibliográficos
Autores principales:	Yang, Shang, Constantin, Oana M., Sachidanandan, Divya, Hofmann, Hannes, Kunz, Tobias C., Kozjak-Pavlovic, Vera, Oertner, Thomas G., Nagel, Georg, Kittel, Robert J., Gee, Christine E., Gao, Shiqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522238/ https://www.ncbi.nlm.nih.gov/pubmed/34663304 http://dx.doi.org/10.1186/s12915-021-01151-9

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