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Continuous variable responses and signal gating form kinetic bases for pulsatile insulin signaling and emergence of resistance
Understanding kinetic control of biological processes is as important as identifying components that constitute pathways. Insulin signaling is central for almost all metazoans, and its perturbations are associated with various developmental disorders, metabolic diseases, and aging. While temporal ph...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
National Academy of Sciences
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522282/ https://www.ncbi.nlm.nih.gov/pubmed/34615716 http://dx.doi.org/10.1073/pnas.2102560118 |