Cargando…
Vitamin B(12) impacts amyloid beta-induced proteotoxicity by regulating the methionine/S-adenosylmethionine cycle
Alzheimer’s disease (AD) is a devastating neurodegenerative disorder with no effective treatment. Diet, as a modifiable risk factor for AD, could potentially be targeted to slow disease onset and progression. However, complexity of the human diet and indirect effects of the microbiome make it challe...
Autores principales: | Lam, Andy B., Kervin, Kirsten, Tanis, Jessica E. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522492/ https://www.ncbi.nlm.nih.gov/pubmed/34592146 http://dx.doi.org/10.1016/j.celrep.2021.109753 |
Ejemplares similares
-
Serum S-adenosylmethionine, but not methionine, increases in response to overfeeding in humans
por: Elshorbagy, A K, et al.
Publicado: (2016) -
Caenorhabditis elegans methionine/S-adenosylmethionine cycle activity is sensed and adjusted by a nuclear hormone receptor
por: Giese, Gabrielle E, et al.
Publicado: (2020) -
Methionine and S-Adenosylmethionine Regulate Monascus Pigments Biosynthesis in Monascus purpureus
por: Yin, Sheng, et al.
Publicado: (2022) -
Perturbation of Methionine/S-adenosylmethionine Metabolism as a Novel Vulnerability in MLL Rearranged Leukemia
por: Barve, Aditya, et al.
Publicado: (2019) -
Enhancing mitochondrial proteostasis reduces amyloid-β proteotoxicity
por: Sorrentino, Vincenzo, et al.
Publicado: (2017)