Radium-223 Treatment in mCRPC Patient with Polycythemia Vera

There have been several studies on the clinical outcomes of Radium-223 treatment in patients with metastatic castration-resistant prostate cancer (mCRPC) who may have an increased risk of hematologic comorbidities. To the best of our knowledge, this is the first study to explore the potential bone m...

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Detalles Bibliográficos
Autores principales: de Angelis, Cristina, Frantellizzi, Viviana, Pontico, Mariano, de Feo, Maria Silvia, Lazri, Julia, de Vincentis, Giuseppe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2021
Materias:
Interesting Image
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522512/
https://www.ncbi.nlm.nih.gov/pubmed/34660164
http://dx.doi.org/10.4274/mirt.galenos.2020.58661
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author de Angelis, Cristina
Frantellizzi, Viviana
Pontico, Mariano
de Feo, Maria Silvia
Lazri, Julia
de Vincentis, Giuseppe
author_facet de Angelis, Cristina
Frantellizzi, Viviana
Pontico, Mariano
de Feo, Maria Silvia
Lazri, Julia
de Vincentis, Giuseppe
author_sort de Angelis, Cristina
collection PubMed
description There have been several studies on the clinical outcomes of Radium-223 treatment in patients with metastatic castration-resistant prostate cancer (mCRPC) who may have an increased risk of hematologic comorbidities. To the best of our knowledge, this is the first study to explore the potential bone marrow adverse effects (AEs) of Radium-223 administered with specific drugs used for hematologic conditions, such as polycythemia vera (PV). We report the case of a patient with mCRPC who was administered a combined treatment of Radium-223 and hydroxyurea for PV, aiming to support clinicians in predicting eventual AEs.
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spelling pubmed-85225122021-10-26 Radium-223 Treatment in mCRPC Patient with Polycythemia Vera de Angelis, Cristina Frantellizzi, Viviana Pontico, Mariano de Feo, Maria Silvia Lazri, Julia de Vincentis, Giuseppe Mol Imaging Radionucl Ther Interesting Image There have been several studies on the clinical outcomes of Radium-223 treatment in patients with metastatic castration-resistant prostate cancer (mCRPC) who may have an increased risk of hematologic comorbidities. To the best of our knowledge, this is the first study to explore the potential bone marrow adverse effects (AEs) of Radium-223 administered with specific drugs used for hematologic conditions, such as polycythemia vera (PV). We report the case of a patient with mCRPC who was administered a combined treatment of Radium-223 and hydroxyurea for PV, aiming to support clinicians in predicting eventual AEs. Galenos Publishing 2021-10 2021-10-15 /pmc/articles/PMC8522512/ /pubmed/34660164 http://dx.doi.org/10.4274/mirt.galenos.2020.58661 Text en ©Copyright 2021 by Turkish Society of Nuclear Medicine | Molecular Imaging and Radionuclide Therapy published by Galenos Yayınevi. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Interesting Image
de Angelis, Cristina
Frantellizzi, Viviana
Pontico, Mariano
de Feo, Maria Silvia
Lazri, Julia
de Vincentis, Giuseppe
Radium-223 Treatment in mCRPC Patient with Polycythemia Vera
title Radium-223 Treatment in mCRPC Patient with Polycythemia Vera
title_full Radium-223 Treatment in mCRPC Patient with Polycythemia Vera
title_fullStr Radium-223 Treatment in mCRPC Patient with Polycythemia Vera
title_full_unstemmed Radium-223 Treatment in mCRPC Patient with Polycythemia Vera
title_short Radium-223 Treatment in mCRPC Patient with Polycythemia Vera
title_sort radium-223 treatment in mcrpc patient with polycythemia vera
topic Interesting Image
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522512/
https://www.ncbi.nlm.nih.gov/pubmed/34660164
http://dx.doi.org/10.4274/mirt.galenos.2020.58661
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