A Case with (68)Ga-FAPI Positive and (18)F-FDG Negative Breast Cancer

A female patient diagnosed of infiltrative breast carcinoma using tru-cut biopsy underwent (18)flourine-fluorodeoxyglucose ((18)F-FDG) positron emission tomography/computed tomography (PET/CT) for staging. The tumor was located in the superior external quadrant of the right breast, and did not exhib...

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Detalles Bibliográficos
Autores principales: Kömek, Halil, Gündoğan, Cihan, Etem, Hülya, Can, Canan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Galenos Publishing 2021
Materias:
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522513/
https://www.ncbi.nlm.nih.gov/pubmed/34661066
http://dx.doi.org/10.4274/mirt.galenos.2021.69926
Descripción
Sumario:A female patient diagnosed of infiltrative breast carcinoma using tru-cut biopsy underwent (18)flourine-fluorodeoxyglucose ((18)F-FDG) positron emission tomography/computed tomography (PET/CT) for staging. The tumor was located in the superior external quadrant of the right breast, and did not exhibit pathological uptake in (18)F-FDG PET/CT. Later, gallium-(68) ((68)Ga) fibroblast activation protein-specific inhibitor (FAPI)-04 PET/CT imaging was performed and the primary tumor showed intense radiotracer accumulation. This presumes that (68)Ga-FAPI PET/CT imaging is superior to (18)F-FDG imaging in detecting the primary tumor in breast cancer, thereby suggesting the replacement of FAPI by (18)F-FDG in breast-cancer staging in the future.

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