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Follow-up Care for Patients Receiving Immune Checkpoint Inhibitors

The rapid advances in cancer immunotherapy using immune checkpoint inhibitors (ICIs) have led to significantly improved survival of patients. But at the same time, it also associates with multiple immune-related adverse events (irAEs). The irAEs can affect a wide range of organs, and induce nonspeci...

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Detalles Bibliográficos
Autores principales: Zhang, Liyan, Lu, Yuhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522586/
https://www.ncbi.nlm.nih.gov/pubmed/34790843
http://dx.doi.org/10.4103/apjon.apjon-2129
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author Zhang, Liyan
Lu, Yuhan
author_facet Zhang, Liyan
Lu, Yuhan
author_sort Zhang, Liyan
collection PubMed
description The rapid advances in cancer immunotherapy using immune checkpoint inhibitors (ICIs) have led to significantly improved survival of patients. But at the same time, it also associates with multiple immune-related adverse events (irAEs). The irAEs can affect a wide range of organs, and induce nonspecific symptoms with delayed onset and prolonged duration that is easily neglected, which may lead to life-threatening disorders. Therefore, follow-up care for patients receiving ICIs for irAEs management has become an essential competency in cancer nursing. There are several guidelines about the management of irAEs, which focused on diagnosis, grading, and treatment. However, studies on relevant follow-up care are rare. Nurses play an important role in follow-up care, whose relevant knowledge and skills are indispensable. Combined with domestic and foreign guidelines and related studies, this paper reviewed the occurrence and characteristics of irAEs and highlighted the contents, timing, models, and effects of follow-up care for patients receiving ICIs, to provide a reference for clinical nursing practice and improve the safety of immunotherapy for patients.
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spelling pubmed-85225862021-11-16 Follow-up Care for Patients Receiving Immune Checkpoint Inhibitors Zhang, Liyan Lu, Yuhan Asia Pac J Oncol Nurs Review Article The rapid advances in cancer immunotherapy using immune checkpoint inhibitors (ICIs) have led to significantly improved survival of patients. But at the same time, it also associates with multiple immune-related adverse events (irAEs). The irAEs can affect a wide range of organs, and induce nonspecific symptoms with delayed onset and prolonged duration that is easily neglected, which may lead to life-threatening disorders. Therefore, follow-up care for patients receiving ICIs for irAEs management has become an essential competency in cancer nursing. There are several guidelines about the management of irAEs, which focused on diagnosis, grading, and treatment. However, studies on relevant follow-up care are rare. Nurses play an important role in follow-up care, whose relevant knowledge and skills are indispensable. Combined with domestic and foreign guidelines and related studies, this paper reviewed the occurrence and characteristics of irAEs and highlighted the contents, timing, models, and effects of follow-up care for patients receiving ICIs, to provide a reference for clinical nursing practice and improve the safety of immunotherapy for patients. Wolters Kluwer - Medknow 2021-10-04 /pmc/articles/PMC8522586/ /pubmed/34790843 http://dx.doi.org/10.4103/apjon.apjon-2129 Text en Copyright: © 2021 Ann & Joshua Medical Publishing Co. Ltd https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Review Article
Zhang, Liyan
Lu, Yuhan
Follow-up Care for Patients Receiving Immune Checkpoint Inhibitors
title Follow-up Care for Patients Receiving Immune Checkpoint Inhibitors
title_full Follow-up Care for Patients Receiving Immune Checkpoint Inhibitors
title_fullStr Follow-up Care for Patients Receiving Immune Checkpoint Inhibitors
title_full_unstemmed Follow-up Care for Patients Receiving Immune Checkpoint Inhibitors
title_short Follow-up Care for Patients Receiving Immune Checkpoint Inhibitors
title_sort follow-up care for patients receiving immune checkpoint inhibitors
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522586/
https://www.ncbi.nlm.nih.gov/pubmed/34790843
http://dx.doi.org/10.4103/apjon.apjon-2129
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