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Disulfide bond formation in microtubule-associated tau protein promotes tau accumulation and toxicity in vivo

Accumulation of microtubule-associated tau protein is thought to cause neuron loss in a group of neurodegenerative diseases called tauopathies. In diseased brains, tau molecules adopt pathological structures that propagate into insoluble forms with disease-specific patterns. Several types of posttra...

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Detalles Bibliográficos
Autores principales:	Saito, Taro, Chiku, Tomoki, Oka, Mikiko, Wada-Kakuda, Satoko, Nobuhara, Mika, Oba, Toshiya, Shinno, Kanako, Abe, Saori, Asada, Akiko, Sumioka, Akio, Takashima, Akihiko, Miyasaka, Tomohiro, Ando, Kanae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2021
Materias:	General Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8522637/ https://www.ncbi.nlm.nih.gov/pubmed/34137825 http://dx.doi.org/10.1093/hmg/ddab162

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